ArticleHuman brain mapping2017
Sensory tractography and robot-quantified proprioception in hemiparetic children with perinatal stroke.
Article in Human brain mapping, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed, 49 citations in OpenAlex.
- Accuracy deficits during robotic time-constrained reaching are related to altered prefrontal cortex activity in children with cerebral palsy.Journal of neuroengineering and rehabilitation · 2024Trial
- Sensorimotor Robotic Measures of tDCS- and HD-tDCS-Enhanced Motor Learning in Children.Neural plasticity · 2018Trial
- Recent Advances in Sensor-Based Upper-Limb and Hand Exoskeletons for Post-Stroke Rehabilitation: A Technical and Biomedical Review.Sensors (Basel, Switzerland) · 2026Review
- White matter microstructure in language tracts in youth with perinatal stroke.Brain imaging and behavior · 2025Article
- Thalamic oscillatory dysrhythmia and disrupted functional connectivity in thalamocortical loops in perinatal stroke.Scientific reports · 2025Article
- Executive functioning, ADHD symptoms and resting state functional connectivity in children with perinatal stroke.Brain imaging and behavior · 2024Article
- Article
- Limb-specific thalamocortical tracts are impaired differently in hemiplegic and diplegic subtypes of cerebral palsy.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- The Effect of Bimanual Intensive Functional Training on Somatosensory Hand Function in Children with Unilateral Spastic Cerebral Palsy: An Observational Study.Journal of clinical medicine · 2023Article
- Neuro-imaging characteristics of sensory impairment in cerebral palsy; a systematic review.Frontiers in rehabilitation sciences · 2023Review
- Identification of proprioceptive thalamocortical tracts in children: comparison of fMRI, MEG, and manual seeding of probabilistic tractography.Cerebral cortex (New York, N.Y. : 1991) · 2022Article
- Structural connectivity of the sensorimotor network within the non-lesioned hemisphere of children with perinatal stroke.Scientific reports · 2022Article
- Frontal interhemispheric structural connectivity, attention, and executive function in children with perinatal stroke.Brain and behavior · 2022Article
- Somatosensory deficits and neural correlates in cerebral palsy: a scoping review.Developmental medicine and child neurology · 2021Article
- Robotic devices for paediatric rehabilitation: a review of design features.Biomedical engineering online · 2021Review
- Head circumference trajectory in children with perinatal stroke.Journal of child neurology · 2021Article
- Perinatal stroke: mapping and modulating developmental plasticity.Nature reviews. Neurology · 2021Review
- Relative independence of upper limb position sense and reaching in children with hemiparetic perinatal stroke.Journal of neuroengineering and rehabilitation · 2021Article
- Developmental neuroplasticity of the white matter connectome in children with perinatal stroke.Neurology · 2020Article
- Tools and Techniques Used With Robotic Devices to Quantify Upper-Limb Function in Typically Developing Children: A Systematic Review.Rehabilitation process and outcome · 2020Review
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Perinatal stroke causes most hemiparetic cerebral palsy, resulting in lifelong disability. We have demonstrated the ability of robots to quantify sensory dysfunction in hemiparetic children but the relationship between such deficits and sensory tract structural connectivity has not been explored. It was aimed to characterize the relationship between the dorsal column medial lemniscus (DCML) pathway connectivity and proprioceptive dysfunction in children with perinatal stroke. Twenty-nine participants (6-19 years old) with MRI-classified, unilateral perinatal ischemic stroke (14 arterial, 15 venous), and upper extremity deficits were recruited from a population-based cohort and compared with 21 healthy controls. Diffusion tensor imaging (DTI) defined DCML tracts and five diffusion properties were quantified: fractional anisotropy (FA), mean, radial, and axial diffusivities (MD, RD, AD), and fiber count. A robotic exoskeleton (KINARM) tested upper limb proprioception in an augmented reality environment. Correlations between robotic measures and sensory tract diffusion parameters were evaluated. Lesioned hemisphere sensory tracts demonstrated lower FA and higher MD, RD, and AD compared with the non-dominant hemisphere of controls. Dominant (contralesional) hemisphere tracts were not different from controls. Both arterial and venous stroke groups demonstrated impairments in proprioception that correlated with lesioned hemisphere DCML tract diffusion properties. Sensory tract connectivity is altered in the lesioned hemisphere of hemiparetic children with perinatal stroke. A correlation between lesioned DCML tract diffusion properties and robotic proprioceptive measures suggests clinical relevance and a possible target for therapeutic intervention. Hum Brain Mapp 38:2424-2440, 2017. © 2017 Wiley Periodicals, Inc.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.