Evidence map›Paper›PMID 28176377›Full record

ArticleMycoses2017

Novel taxa of thermally dimorphic systemic pathogens in the Ajellomycetaceae (Onygenales).

Karolina Dukik, Jose F Muñoz, Yanping Jiang, Peiying Feng, Lynne Sigler, J Benjamin Stielow, Joanna Freeke, Azadeh Jamalian, Bert Gerrits van den Ende, Juan G McEwen and 9 more

Open access · greenAbstract read
In one paragraph

Article in Mycoses, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
85citing papers in PubMed, 2 pooled it
8.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

85 citing papers in PubMed, 2 syntheses or guidelines pooled it, 142 citations in OpenAlex.

  1. Pooled it
  2. Name Changes for Fungi of Medical Importance, 2016-2017.Journal of clinical microbiology · 2019
    Pooled it
  3. Article
  4. Article
  5. Article
  6. Tools for genetic manipulation of the endemic fungal pathogen,bioRxiv : the preprint server for biology · 2025
    Article
  7. AutochthonousDermatology reports · 2025
    Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Systemic Mycoses by Novel Onygenalean Fungal PathogensOpen forum infectious diseases · 2024
    Article
  17. Review
  18. Article
  19. Article
  20. The pathogenesis of experimental Emergomycosis in mice.PLoS neglected tropical diseases · 2024
    Article

25 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 12 institutions in 9 countries.

Karolina DukikCBS-KNAW Fungal Biodiversity Centre, Utrecht, The Netherlands.ORCID http://orcid.org/0000-0002-5963-7079
Jose F MuñozBroad Institute of MIT and Harvard, Cambridge, MA, USA.
Yanping JiangCBS-KNAW Fungal Biodiversity Centre, Utrecht, The Netherlands.
Peiying FengCBS-KNAW Fungal Biodiversity Centre, Utrecht, The Netherlands.
Lynne SiglerUniversity of Alberta Microfungus Collection and Herbarium and Biological Sciences, Edmonton, AB, Canada.
J Benjamin StielowCBS-KNAW Fungal Biodiversity Centre, Utrecht, The Netherlands.
Joanna FreekeCBS-KNAW Fungal Biodiversity Centre, Utrecht, The Netherlands.
Azadeh JamalianCBS-KNAW Fungal Biodiversity Centre, Utrecht, The Netherlands.
Bert Gerrits van den EndeCBS-KNAW Fungal Biodiversity Centre, Utrecht, The Netherlands.
Juan G McEwenCellular and Molecular Biology Unit, Corporación para Investigaciones Biológicas (CIB), Medellín, Colombia.
Oliver K ClayCellular and Molecular Biology Unit, Corporación para Investigaciones Biológicas (CIB), Medellín, Colombia.
Ilan S SchwartzFaculty of Medicine and Health Sciences, Epidemiology for Global Health Institute, University of Antwerp, Antwerp, Belgium.
Nelesh P GovenderUniversity of Cape Town, Cape Town, South Africa.
Tsidiso G MaphangaNational Institute for Communicable Diseases, Johannesburg, South Africa.
Christina A CuomoBroad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID http://orcid.org/0000-0002-5778-960X
Leandro F MorenoCBS-KNAW Fungal Biodiversity Centre, Utrecht, The Netherlands.
Chris KenyonUniversity of Cape Town, Cape Town, South Africa.
Andrew M BormanPHE UK Mycology Reference Laboratory, Bristol, UK.
Sybren de HoogCBS-KNAW Fungal Biodiversity Centre, Utrecht, The Netherlands.
Westerdijk Fungal Biodiversity Institute · NLThermo Fisher Scientific (Netherlands) · NLBroad Institute · USNational Health Laboratory Service · ZACorporación para Investigaciones Biológicas · COGuiyang Medical University · CNIndustrial Phycology (United Kingdom) · GBSun Yat-sen University · CNUniversidad de Antioquia · COUniversity of Alberta · CAUniversity of Antwerp · BEUniversity of Cape Town · ZA

Funding

Viral Genomics: evolution, spread, and host interactionsU19AI110818 · NIAID · BROAD INSTITUTE, INC. · PI CUOMO, CHRISTINA A · 2014 to 2024
$66.5M
NIAID NIH HHS HHSN272200900018CNIAID NIH HHS U19 AI110818
6 · The paper itself

Abstract

Recent discoveries of novel systemic fungal pathogens with thermally dimorphic yeast-like phases have challenged the current taxonomy of the Ajellomycetaceae, a family currently comprising the genera Blastomyces, Emmonsia, Emmonsiellopsis, Helicocarpus, Histoplasma, Lacazia and Paracoccidioides. Our morphological, phylogenetic and phylogenomic analyses demonstrated species relationships and their specific phenotypes, clarified generic boundaries and provided the first annotated genome assemblies to support the description of two new species. A new genus, Emergomyces, accommodates Emmonsia pasteuriana as type species, and the new species Emergomyces africanus, the aetiological agent of case series of disseminated infections in South Africa. Both species produce small yeast cells that bud at a narrow base at 37°C and lack adiaspores, classically associated with the genus Emmonsia. Another novel dimorphic pathogen, producing broad-based budding cells at 37°C and occurring outside North America, proved to belong to the genus Blastomyces, and is described as Blastomyces percursus.

Indexed as

BlastomycesChrysosporiumGenome, FungalHistoplasmaHumansMicroscopyMyceliumMycosesNorth AmericaOnygenalesPhenotypePhylogenySequence Analysis, DNASouth AfricaSpores, FungalAjellomycetaceaeBlastomycesEmergomycesEmmonsiagenomicsphylogeny

Identifiers

PMID28176377
PMCPMC5775888
OpenAlexW2587328382

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.