Evidence map›Paper›PMID 28176332›Full record

ArticleClinical and experimental immunology2017

Low-dose interleukin-2 promotes STAT-5 phosphorylation, T

H C Jeffery, L E Jeffery, P Lutz, M Corrigan, G J Webb, G M Hirschfield, D H Adams, Y H Oo

Open access · hybridAbstract read
In one paragraph

Article in Clinical and experimental immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 64 citations in OpenAlex.

  1. Article
  2. Multifaceted Roles of IL-26 in Physiological and Pathological Conditions.International journal of molecular sciences · 2025
    Review
  3. Article
  4. Induction of high numbers of TBMC immunology · 2025
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. Phenotypic and Functional Studies of Human Treg Cell Subpopulations.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
  13. Review
  14. Review
  15. Review
  16. Review
  17. Pathogenesis of Autoimmune Hepatitis-Cellular and Molecular Mechanisms.International journal of molecular sciences · 2021
    Review
  18. Article
  19. Functional heterogeneity of CD4Seminars in immunopathology · 2021
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

H C JefferyCentre for Liver Research and National Institute for Health Research Liver Biomedical Research Unit, Institute of Immunology and Immunotherapy, University of Birmingham, UK.
L E JefferyInstitute of Metabolism and Systems Research, University of Birmingham, UK.
P LutzCentre for Liver Research and National Institute for Health Research Liver Biomedical Research Unit, Institute of Immunology and Immunotherapy, University of Birmingham, UK.
M CorriganCentre for Liver Research and National Institute for Health Research Liver Biomedical Research Unit, Institute of Immunology and Immunotherapy, University of Birmingham, UK.
G J WebbCentre for Liver Research and National Institute for Health Research Liver Biomedical Research Unit, Institute of Immunology and Immunotherapy, University of Birmingham, UK.
G M HirschfieldCentre for Liver Research and National Institute for Health Research Liver Biomedical Research Unit, Institute of Immunology and Immunotherapy, University of Birmingham, UK.
D H AdamsCentre for Liver Research and National Institute for Health Research Liver Biomedical Research Unit, Institute of Immunology and Immunotherapy, University of Birmingham, UK.
Y H OoCentre for Liver Research and National Institute for Health Research Liver Biomedical Research Unit, Institute of Immunology and Immunotherapy, University of Birmingham, UK.
University of Birmingham · GBNIHR Birmingham Liver Biomedical Research Unit · GBUniversity Hospitals Birmingham NHS Foundation Trust · GB

Funding

Medical Research Council G0300101Medical Research Council G0300102Medical Research Council G0400496Medical Research Council G0700301Medical Research Council G0802577Medical Research Council G1002552Medical Research Council MC_PC_14123Medical Research Council MR/M001911/1Medical Research Council MR/M009157/1
6 · The paper itself

Abstract

CD4

Indexed as

AdultAgedAutoimmune DiseasesBiomarkersCase-Control StudiesCells, CulturedCTLA-4 AntigenFemaleFlow CytometryHumansInterleukin-2Liver DiseasesMaleMiddle AgedPhosphorylationRecombinant ProteinsaldesleukinBiomarkersCTLA-4 AntigenCTLA4 protein, humanInterleukin-2Recombinant ProteinsSTAT5 Transcription Factorautoimmune liver diseaseBcl-2CTLA-4interleukin-2regulatory T cellsSTAT-5

Identifiers

PMID28176332
PMCPMC5422719
OpenAlexW2587006481

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.