ArticleJournal of the American Geriatrics Society2017
Cognitive Differences between Men and Women who Fracture their Hip and Impact on Six-Month Survival.
Article in Journal of the American Geriatrics Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04626934 (Can Specific Cognitive Intervention With Post-Acute Cognitively Impaired Hip Fracture Patients Improve Rehabilitation Outcome), which is not on this map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Can Specific Cognitive Intervention With Post-Acute Cognitively Impaired Hip Fracture Patients Improve Rehabilitation Outcome
Who cites it
16 citing papers in PubMed.
- Impact of a Multi-Component Home-Based Physical Therapy Intervention on Cognitive Outcomes: Results From the CAP Randomized Controlled Trial.Journal of aging and health · 2026Trial
- Sex modified the association between cognitive impairment and 1-year mortality in older adults with hip fractures.Scientific reports · 2025Article
- Mortality and Function After Hip Fracture or Pneumonia in People With and Without Dementia.Journal of the American Geriatrics Society · 2025Article
- Trajectories of Recovery Following Traumatic Brain Injury Among Older Medicare Beneficiaries.Journal of neurotrauma · 2024Article
- Associations of sex, Alzheimer's disease and related dementias, and days alive and at home among older Medicare beneficiaries recovering from hip fracture.Journal of the American Geriatrics Society · 2023Article
- Prediction of 3-Year Survival in Patients with Cognitive Impairment Based on Demographics, Neuropsychological Data, and Comorbidities: A Prospective Cohort Study.Brain sciences · 2023Article
- Long-term sex differences in all-cause and infection-specific mortality post hip fracture.Journal of the American Geriatrics Society · 2022Article
- Incidence of potentially disruptive medical and social events in older adults with and without dementia.Journal of the American Geriatrics Society · 2022Article
- Reduction of neuroinflammation alleviated mouse post bone fracture and stroke memory dysfunction.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2021Article
- Neurocognitive measures predict voluntary stepping performance in older adults post-hip fracture.Clinical biomechanics (Bristol, Avon) · 2021Article
- Bone Fracture Enhanced Blood-Brain Barrier Breakdown in the Hippocampus and White Matter Damage of Stroke Mice.International journal of molecular sciences · 2020Article
- Fracture shortly before stroke in mice leads to hippocampus inflammation and long-lasting memory dysfunction.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2020Article
- Risk of Mortality in Individuals with Hip Fracture and Traumatic Brain Injury.Journal of the American Geriatrics Society · 2019Article
- Impact of Bone Fracture on Ischemic Stroke Recovery.International journal of molecular sciences · 2018Review
- Not the Last Word: Bhandari's Paradox.Clinical orthopaedics and related research · 2018Article
- Editorial: Orthogeriatrics and Hip Fractures.The journal of nutrition, health & aging · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
objectivesThere is limited research in cognition and its relationship to mortality after hip fracture among men compared to women. Therefore, the goals of this study were to: (1) compare men and women who fractured their hip on cognition after hospital discharge, and (2) examine the impact of cognition on the differential risk of 6-month mortality between men and women post fracture.
designProspective cohort study.
settingEight hospitals in Baltimore, Maryland.
participantsFrequency matched 168 male and 171 female hip fracture patients, ages 65 or older, living in the community before fracture. MEASUREMENTS: Cognition assed by Modified Mini-Mental State Examination (3MS, and derived MMSE score), Hooper Visual Organization test (HVOT), and Trail-making test (Trails A & B) within 22 days of hospital admission, and 6-month mortality.
resultsMen had more impaired cognitive scores on 3MS, MMSE, HVOT, and Trails A (P < .05) at baseline. These statistically significant differences between men and women remained on MMSE and HVOT after controlling for pre-fracture dementia, in-hospital delirium, age, education, race, and comorbidity. Men had higher 6-month mortality rates (HR = 4.4, P < .001). Cognitive measures were also significantly associated with mortality, including 3MS, HVOT, and Trails B. Among the cognitive measures, higher 3MS was most protective for mortality (HR = 0.98, P < .001), both unadjusted and adjusted for other cognitive scales, comorbidity, delirium, and pre-existing dementia. The highest mortality was among men with 3MS<78, with 26.3% dying within 6 months. The effects of cognition on mortality did not differ by sex.
conclusionMen display greater levels of cognitive impairment within the first 22 days of hip fracture than women, and cognitive limitations increase the risk of mortality in both men and women.
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