Evidence map›Paper›PMID 28176271›Full record

ReviewTopics in current chemistry (Cham)2017

Proteins in Ionic Liquids: Current Status of Experiments and Simulations.

Christian Schröder

Abstract readReview
In one paragraph

Review in Topics in current chemistry (Cham), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Heterogeneous Nucleation in Protein Crystallization.Biomimetics (Basel, Switzerland) · 2023
    Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Advances in Membrane-Bound Catechol-International journal of molecular sciences · 2022
    Article
  17. Energy Transport alongMaterials (Basel, Switzerland) · 2022
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Christian SchröderFaculty of Chemistry, Department of Computational Biological Chemistry, University of Vienna, Vienna, Austria. christian.schroeder@univie.ac.at.ORCID http://orcid.org/0000-0002-2167-5096

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the last two decades, while searching for interesting applications of ionic liquids as potent solvents, their solvation properties and their general impact on biomolecules, and in particular on proteins, gained interest. It turned out that ionic liquids are excellent solvents for protein refolding and crystallization. Biomolecules showed increased solubilities and stabilities, both operational and thermal, in ionic liquids, which also seem to prevent self-aggregation during solubilization. Biomolecules can be immobilized, e.g. in highly viscous ionic liquids, for particular biochemical processes and can be designed to some extent by the proper choice of the ionic liquid cations and anions, which can be characterized by the Hofmeister series.

Indexed as

Ionic LiquidsModels, MolecularMolecular StructureProtein RefoldingProteinsSolventsIonic LiquidsProteinsSolventsCrystallizationDenaturationDetectionDirect and reversed Hofmeister seriesExtractionIonic liquidSeparationSolubilityStabilization

Identifiers

PMID28176271
PMCPMC5480425

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.