ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2018
Partial volume correction for improved PET quantification in
Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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23 citing papers in PubMed, 38 citations in OpenAlex.
- Direct estimation of activity concentration in regional voxels with application toMedical physics · 2026Article
- Critical review of partial volume correction methods in PET and SPECT imaging: benefits, pitfalls, challenges, and future outlook.European journal of nuclear medicine and molecular imaging · 2026Review
- Positron emission tomography and its role in the assessment of vulnerable plaques in comparison to other imaging modalities.Frontiers in medicine · 2023Review
- Longitudinal analysis of atherosclerotic plaques evolution: anJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- Accuracy of PET quantification in [Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- Assessment of different quantification metrics of [Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- Iterative reconstruction incorporating background correction improves quantification of [Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- Fluorine-18 fluorodeoxyglucose positron emission tomography-based textural features for prediction of event prone carotid atherosclerotic plaques.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- Optimizing arterialJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- Clinical implications ofJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- Vulnerable plaque imaging usingThe British journal of radiology · 2020Review
- PET-derived bone information from 18F-sodium fluoride: A perfect match for whole-body PET/MR attenuation correction?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Article
- Comparison of Correction Techniques for the Spill in Effect in Emission Tomography.IEEE transactions on radiation and plasma medical sciences · 2020Article
- Atherosclerosis imaging withEuropean journal of nuclear medicine and molecular imaging · 2020Review
- Analytical quantification of aortic valve 18F-sodium fluoride PET uptake.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Article
- Coronary artery 18F-NaF PET analysis with the use of an elastic motion correction software.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Article
- Whole-Body Atherosclerosis Imaging by Positron Emission Tomography/Magnetic Resonance Imaging: From Mice to Nonhuman Primates.Arteriosclerosis, thrombosis, and vascular biology · 2020Review
- Imaging Atherosclerosis by PET, With Emphasis on the Role of FDG and NaF as Potential Biomarkers for This Disorder.Frontiers in physiology · 2020Review
- Hype or HopeCirculation. Cardiovascular imaging · 2019Article
- Review of cardiovascular imaging in the Journal of Nuclear Cardiology 2018. Part 1 of 2: Positron emission tomography, computed tomography, and magnetic resonance.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Review
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAccurate quantification of plaque imaging using
methodsPVC of PET data was implemented by the use of a local projection (LP) method. LP-based PVC was evaluated with an image quality (NEMA) and with a thorax phantom with "plaque-type" lesions of 18-36 mL. The validated PVC method was then applied to a cohort of 17 patients, each with at least one plaque in the carotid or ascending aortic arteries. In total, 51 calcified (HU > 110) and 16 non-calcified plaque lesions (HU < 110) were analyzed. The lesion-to-background ratio (LBR) and the relative change of LBR (ΔLBR) were measured on PET.
resultsFollowing PVC, LBR of the spheres (NEMA phantom) was within 10% of the original values. LBR of the thoracic lesions increased by 155% to 440% when the LP-PVC method was applied to the PET images. In patients, PVC increased the LBR in both calcified [mean = 78% (-8% to 227%)] and non-calcified plaques [mean = 41%, (-9%-104%)].
conclusionsPVC helps to improve LBR of plaque-type lesions in both phantom studies and clinical patients. Better results were obtained when the PVC method was applied to images reconstructed with point spread function modeling.
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