ArticleBreast cancer research and treatment2017
Adiposity, post-diagnosis weight change, and risk of cardiovascular events among early-stage breast cancer survivors.
Article in Breast cancer research and treatment, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03935282 (Assessing Effectiveness and Implementation of an EHR Tool to Assess Heart Health Among Survivors), which is not on this map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Assessing Effectiveness and Implementation of an EHR Tool to Assess Heart Health Among Survivors (AH-HA)
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- Optimising weight-loss interventions in cancer patients-A systematic review and network meta-analysis.PloS one · 2021Pooled it
- Low-touch, team-based care for co-morbidity management in cancer patients: the ONE TEAM randomized controlled trial.BMC family practice · 2021Trial
- A randomized trial of exercise and diet on body composition in survivors of breast cancer with overweight or obesity.Breast cancer research and treatment · 2021Trial
- The Yale Fitness Intervention Trial in female cancer survivors: Cardiovascular and physiological outcomes.Heart & lung : the journal of critical careTrial
- Polygenic risk of coronary artery disease for long-term survivors of breast cancer.Journal of the National Cancer Institute · 2025Article
- Changes in health behaviors and risk of depression after breast cancer diagnosis and treatment: a nationwide cohort study.Journal of cancer survivorship : research and practice · 2025Article
- Weight change and cardiovascular disease incidence in breast cancer survivors: a nationwide cohort study.Breast cancer research and treatment · 2025Article
- Life's Essential 8 and Cardiovascular Disease in Breast Cancer Survivors.Current cardiology reports · 2025Review
- Factors associated with weight gain in pre- and post-menopausal women receiving adjuvant endocrine therapy for breast cancer.Journal of cancer survivorship : research and practice · 2024Article
- Article
- The relation between excess adiposity and breast cancer in women: Clinical implications and management.Critical reviews in oncology/hematology · 2024Review
- Post-diagnosis weight trajectories and mortality among women with breast cancer.NPJ breast cancer · 2023Article
- Changes in body composition and subsequent cardiovascular disease risk among 5-year breast cancer survivors.Frontiers in cardiovascular medicine · 2023Article
- Cardiometabolic Comorbidities in Cancer Survivors:JACC. CardioOncology · 2022Review
- Article
- Evidence-based prediction and prevention of cardiovascular morbidity in adults treated for cancer.Cardio-oncology (London, England) · 2021Review
- Breast Cancer Survivors Undergoing Endocrine Therapy Have a Worrying Risk Factor Profile for Cardiovascular Diseases.Nutrients · 2021Article
- Risk of coronary heart disease among cancer survivors with different prediagnosis body mass index.Scientific reports · 2021Article
- Cardiovascular Assessment Tool for Breast Cancer Survivors and Oncology Providers: Usability Study.JMIR cancer · 2021Article
- Visceral obesity and incident cancer and cardiovascular disease: An integrative review of the epidemiological evidence.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
purposeLittle research examines whether adiposity or post-diagnosis weight changes influence Cardiovascular disease (CVD) among breast cancer patients for whom effects may differ due to treatment and recovery.
methodsWe studied Stage I-III breast cancer survivors 18 to <80 years, without pre-existing CVD, diagnosed from 1997 to 2013 at Kaiser Permanente. Women reported weight at diagnosis and weight and waist circumference (WC) around 24 months post diagnosis. Using Cox models for time to incident coronary artery disease, heart failure, valve abnormality, arrhythmia, stroke, or CVD death, we examined at-diagnosis body mass index (BMI, n = 3109) and post-diagnosis WC (n = 1898) and weight change (n = 1903, stable, ±5 to <10-lbs or ±≥10-lbs).
resultsMean (SD) age was 57 (11) years, and BMI was 28 (6) kg-m
conclusionExtreme adiposity and any elevation in WC increased risk of CVD among breast cancer survivors; however, changes in weight in the early post-diagnosis period were not associated with CVD. Survivors with high WC and existing CVD risk factors should be monitored.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.