Evidence map›Paper›PMID 28176160›Full record

ArticleVirus genes2017

A novel Enterovirus 96 circulating in China causes hand, foot, and mouth disease.

Yi Xu, Yisuo Sun, Jinmin Ma, Shuru Zhou, Wei Fang, Jiawei Ye, Limei Tan, Jingkai Ji, Dan Luo, Liqiang Li and 8 more

Abstract read
PubMed Publisher
In one paragraph

Article in Virus genes, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Yi XuDepartment of Infectious Disease, Guangzhou Women and Children's Medical Center, Jinsui Road No. 9, Guangzhou, 510120, China.
Yisuo SunBGI-Shenzhen, Shenzhen, 518083, China.
Jinmin MaBGI-Shenzhen, Shenzhen, 518083, China.
Shuru ZhouDepartment of Infectious Disease, Guangzhou Women and Children's Medical Center, Jinsui Road No. 9, Guangzhou, 510120, China.
Wei FangBGI-Shenzhen, Shenzhen, 518083, China.
Jiawei YeDepartment of Infectious Disease, Guangzhou Women and Children's Medical Center, Jinsui Road No. 9, Guangzhou, 510120, China.
Limei TanDepartment of Infectious Disease, Guangzhou Women and Children's Medical Center, Jinsui Road No. 9, Guangzhou, 510120, China.
Jingkai JiBGI-Shenzhen, Shenzhen, 518083, China.
Dan LuoDepartment of Infectious Disease, Guangzhou Women and Children's Medical Center, Jinsui Road No. 9, Guangzhou, 510120, China.
Liqiang LiBGI-Shenzhen, Shenzhen, 518083, China.
Jiandong LiBGI-Shenzhen, Shenzhen, 518083, China.
Chunxiao FangDepartment of Infectious Disease, Guangzhou Women and Children's Medical Center, Jinsui Road No. 9, Guangzhou, 510120, China.
Na PeiBGI-Shenzhen, Shenzhen, 518083, China.
Shuo ShiBGI-Shenzhen, Shenzhen, 518083, China.
Xin LiuBGI-Shenzhen, Shenzhen, 518083, China.
Hui JiangBGI-Shenzhen, Shenzhen, 518083, China.
Sitang GongDepartment of Infectious Disease, Guangzhou Women and Children's Medical Center, Jinsui Road No. 9, Guangzhou, 510120, China. sitangg@126.com.
Xun XuBGI-Shenzhen, Shenzhen, 518083, China. xuxun@genomics.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Enterovirus 96 (EV-96) is a recently described member of the species Enterovirus C and is associated with paralysis and myelitis. In this study, using metagenomic sequencing, we identified a new enterovirus 96 strain (EV-96-SZ/GD/CHN/2014) as the sole pathogen causing hand, foot, and mouth disease (HFMD). A genomic comparison showed that EV-96-SZ/GD/CHN/2014 is most similar to the EV-96-05517 strain (85% identity), which has also been detected in Guangdong Province. This is the first time that metagenomic sequencing has been used to identify an EV-96 strain shown to be associated with HFMD.

Indexed as

Child, PreschoolChinaEnterovirusEnterovirus C, HumanEvolution, MolecularFecesGenome, ViralGenotypeHand, Foot and Mouth DiseaseHumansMaleMetagenomicsPhylogenyRNA, ViralSequence AnalysisSerotypingRNA, ViralEnterovirus 96EvolutionGenome sequenceHFMDMetagenomics

Identifiers

PMID28176160

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.