Evidence map›Paper›PMID 28176151›Full record

ArticleEndocrine pathology2017

Frequent BRAF

Naoki Oishi, Tetsuo Kondo, Tadao Nakazawa, Kunio Mochizuki, Tomohiro Inoue, Kazunari Kasai, Ippei Tahara, Tomonori Yabuta, Mitsuyoshi Hirokawa, Akira Miyauchi and 1 more

Abstract read
PubMed Publisher
In one paragraph

Article in Endocrine pathology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 2 pooled it
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 2 syntheses or guidelines pooled it, 50 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Incidence ofThe Journal of international medical research · 2019
    Trial
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Molecular Landscape of Pediatric Thyroid Cancer: A Review.Diagnostics (Basel, Switzerland) · 2022
    Review
  13. Article
  14. Article
  15. Article
  16. TheCancers · 2021
    Article
  17. Article
  18. Molecular pathogenesis of pediatric thyroid carcinoma.Journal of radiation research · 2021
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Naoki OishiDepartment of Pathology, University of Yamanashi, Chuo, Yamanashi, 409-3898, Japan.
Tetsuo KondoDepartment of Pathology, University of Yamanashi, Chuo, Yamanashi, 409-3898, Japan.
Tadao NakazawaDepartment of Pathology, University of Yamanashi, Chuo, Yamanashi, 409-3898, Japan.
Kunio MochizukiDepartment of Pathology, University of Yamanashi, Chuo, Yamanashi, 409-3898, Japan.
Tomohiro InoueDepartment of Pathology, University of Yamanashi, Chuo, Yamanashi, 409-3898, Japan.
Kazunari KasaiDepartment of Pathology, University of Yamanashi, Chuo, Yamanashi, 409-3898, Japan.
Ippei TaharaDepartment of Pathology, University of Yamanashi, Chuo, Yamanashi, 409-3898, Japan.
Tomonori YabutaDepartment of Surgery, Kuma Hospital, Kobe, Hyogo, 650-0011, Japan.
Mitsuyoshi HirokawaDepartment of Diagnostic Pathology, Kuma Hospital, Kobe, Hyogo, 650-0011, Japan.
Akira MiyauchiDepartment of Surgery, Kuma Hospital, Kobe, Hyogo, 650-0011, Japan.
Ryohei KatohDepartment of Pathology, University of Yamanashi, Chuo, Yamanashi, 409-3898, Japan. rkatoh@yamanashi.ac.jp.
University of Yamanashi · JPKuma Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pediatric papillary thyroid carcinoma (PTC) has unique features but requires further genetic investigation. Moreover, there has been increasing concern about the risk for pediatric PTC in Japan after the Fukushima accident. This study aims to evaluate the frequencies of BRAF and TERT promoter mutations and to examine their significance in non-radiation-associated pediatric PTCs in Japan. We enrolled 81 pediatric PTC patients aged ≤20 years. The control group included 91 adult PTCs from patients >20 years old. BRAF and TERT mutations were analyzed by allele-specific-PCR and/or Sanger sequencing. Compared with adult PTCs, pediatric PTCs exhibited larger tumor size, more frequent lymph node metastasis, and less classical histology. The prevalence of BRAF

Indexed as

AdolescentCarcinoma, PapillaryChildFemaleHumansJapanMaleMutationPromoter Regions, GeneticProto-Oncogene Proteins B-rafTelomeraseThyroid Cancer, PapillaryThyroid NeoplasmsYoung AdultBRAF protein, humanProto-Oncogene Proteins B-rafTelomeraseTERT protein, humanAdultBRAFMutationPapillary thyroid carcinomaPediatricTERT

Identifiers

PMID28176151
OpenAlexW2586300812

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.