ReviewGenes and environment : the official journal of the Japanese Environmental Mutagen Society2017
Transgenic rat models for mutagenesis and carcinogenesis.
Review in Genes and environment : the official journal of the Japanese Environmental Mutagen Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 45 citations in OpenAlex.
- Functional roles of interstitial cells of Cajal in the GI tract of rats.American journal of physiology. Gastrointestinal and liver physiology · 2025Article
- Comparative Analysis of Estragole, Methyleugenol, Myristicin, and Elemicin Regarding Micronucleus Formation in V79 Cells.Molecules (Basel, Switzerland) · 2025Article
- Genetic models of fibrillinopathies.Genetics · 2024Review
- XLRS Rat with Rs1Genes · 2022Article
- Myristicin and Elemicin: Potentially Toxic Alkenylbenzenes in Food.Foods (Basel, Switzerland) · 2022Review
- Induced mammary cancer in rat models: pathogenesis, genetics, and relevance to female breast cancer.Journal of mammary gland biology and neoplasia · 2022Review
- Mutagenicity of carcinogenic heterocyclic amines in Salmonella typhimurium YG strains and transgenic rodents including gpt delta.Genes and environment : the official journal of the Japanese Environmental Mutagen Society · 2021Review
- New homozygous gpt delta transgenic rat strain improves an efficiency of the in vivo mutagenicity assay.Genes and environment : the official journal of the Japanese Environmental Mutagen Society · 2021Article
- Breast cancer animal models and applications.Zoological research · 2020Review
- The Accumulation and Metabolism Characteristics of Rare Earth Elements in Sprague-Dawley Rats.International journal of environmental research and public health · 2020Article
- Modulation ofChemical research in toxicology · 2020Article
- Thresholds of Genotoxic and Non-Genotoxic Carcinogens.Toxicological research · 2018Review
- Change over time of the mutagenicity in the lungs ofGenes and environment : the official journal of the Japanese Environmental Mutagen Society · 2018Article
- Mechanism of Error-Free DNA Replication Past Lucidin-Derived DNA Damage by Human DNA Polymerase κ.Chemical research in toxicology · 2017Article
- A Simple and Easily Reproducible Model of Reversible Obstructive Jaundice in Rats.In vivo (Athens, Greece)Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Rats are a standard experimental animal for cancer bioassay and toxicological research for chemicals. Although the genetic analyses were behind mice, rats have been more frequently used for toxicological research than mice. This is partly because they live longer than mice and induce a wider variety of tumors, which are morphologically similar to those in humans. The body mass is larger than mice, which enables to take samples from organs for studies on pharmacokinetics or toxicokinetics. In addition, there are a number of chemicals that exhibit marked species differences in the carcinogenicity. These compounds are carcinogenic in rats but not in mice. Such examples are aflatoxin B
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.