ArticleFrontiers in cellular neuroscience2017
Deep Sequencing of the Human Retinae Reveals the Expression of Odorant Receptors.
Article in Frontiers in cellular neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 24 citations in OpenAlex.
- Transcriptomic Profiling of the Human Retina Reveals Inflammatory and Metabolic Signatures Associated With Clinical Severity After Retinal Detachment.Investigative ophthalmology & visual science · 2026Article
- Convergent reduction of olfactory genes and olfactory bulb size in mammalian species at altitude.Current biology : CB · 2025Article
- Olfactory Receptors and Tumorigenesis: Implications for Diagnosis and Targeted Therapy.Cell biochemistry and biophysics · 2025Review
- Polymorphic pseudogenes in the human genome - a comprehensive assessment.Human genetics · 2024Article
- Olfactory Receptors as an Emerging Chemical Sensing Scaffold.Biochemistry · 2023Review
- Distinct sets of olfactory receptors highly expressed in different human tissues evaluated by meta-transcriptome analysis: Association of OR10A6 in skin with keratinization.Frontiers in cell and developmental biology · 2023Article
- Article
- Microbiota Signals during the Neonatal Period Forge Life-Long Immune Responses.International journal of molecular sciences · 2021Review
- Functional Characterization of Olfactory Receptors in the Thyroid Gland.Frontiers in physiology · 2021Article
- A Rose Extract Protects the Skin against Stress Mediators: A Potential Role of Olfactory Receptors.Molecules (Basel, Switzerland) · 2020Article
- Immunocytochemical Localization of Olfactory-signaling Molecules in Human and Rat Spermatozoa.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2020Article
- Elevated COGlobal change biology · 2019Article
- Therapeutic potential of ectopic olfactory and taste receptors.Nature reviews. Drug discovery · 2019Review
- Odorant Receptor 51E2 Agonist β-ionone Regulates RPE Cell Migration and Proliferation.Frontiers in physiology · 2017Article
Corrections and comments
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Authors and funding
13 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Several studies have demonstrated that the expression of odorant receptors (ORs) occurs in various tissues. These findings have served as a basis for functional studies that demonstrate the potential of ORs as drug targets for a clinical application. To the best of our knowledge, this report describes the first evaluation of the mRNA expression of ORs and the localization of OR proteins in the human retina that set a stage for subsequent functional analyses. RNA-Sequencing datasets of three individual neural retinae were generated using Next-generation sequencing and were compared to previously published but reanalyzed datasets of the peripheral and the macular human retina and to reference tissues. The protein localization of several ORs was investigated by immunohistochemistry. The transcriptome analyses detected an average of 14 OR transcripts in the neural retina, of which
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