Evidence map›Paper›PMID 28174515›Full record

ArticleFrontiers in neuroscience2017

Upregulation of Bcl-2 and Its Promoter Signals in CD4+ T Cells during Neuromyelitis Optica Remission.

Tao Yang, Su Wang, Xiao Yang, Qi Zheng, Lei Wang, Qian Li, Mingyan Wei, Zongpan Du, Yongping Fan

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Tao YangDepartment of Traditional Chinese Medicine, Beijing Tiantan Hospital, Capital Medical University Beijing, China.
Su WangDepartment of Tumor Radiotherapy, Hiser Medical Center of Qingdao Qingdao, China.
Xiao YangSchool of Management Science and Engineering, Shandong University of Finance and Economics Jinan, China.
Qi ZhengDepartment of Oncology, Guang An Men Hospital of China Academy of Chinese Medical SciencesBeijing, China; School of Traditional Chinese Medicine, Capital Medical UniversityBeijing, China.
Lei WangSchool of Traditional Chinese Medicine, Capital Medical University Beijing, China.
Qian LiDepartment of Traditional Chinese Medicine, Beijing Tiantan Hospital, Capital Medical University Beijing, China.
Mingyan WeiDepartment of Traditional Chinese Medicine, Beijing Tiantan Hospital, Capital Medical University Beijing, China.
Zongpan DuDepartment of Traditional Chinese Medicine, Beijing Tiantan Hospital, Capital Medical University Beijing, China.
Yongping FanDepartment of Traditional Chinese Medicine, Beijing Tiantan Hospital, Capital Medical University Beijing, China.
Capital Medical University · CNQingdao Center of Resource Chemistry and New Materials · CNShandong University of Finance and Economics · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The homeostatic balance between production and elimination of CD4+ T cells in peripheral blood plays an important role in patients with neuromyelitis optica (NMO). The objective of the present study was to evaluate the anti-apoptosis genes Bcl-2 and its promoter signal (nuclear factor kappa-light-chain-enhancer of activated B cells, NFκB) in CD4+ T cells. Healthy subjects (HS,

Indexed as

Bcl-2MAP3K7multiple sclerosisneuromyelitis opticaNFκB

Identifiers

PMID28174515
PMCPMC5258721
OpenAlexW2581721005

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.