Evidence map›Paper›PMID 28174304›Full record

ArticleThe Journal of biological chemistry2017

The Pyruvate and α-Ketoglutarate Dehydrogenase Complexes of

Nathaniel R Glasser, Benjamin X Wang, Julie A Hoy, Dianne K Newman

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 50 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Decoding in-cell respiratory enzyme dynamics by label-free in situ electrochemistry.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Bioenergetic suppression by redox-active metabolites promotes antibiotic tolerance inProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  11. Metabolic Reprogramming ofJournal of proteome research · 2024
    Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. The chemical ecology of coumarins and phenazines affects iron acquisition by pseudomonads.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Nathaniel R GlasserFrom the Divisions of Biology and Biological Engineering and.
Benjamin X WangFrom the Divisions of Biology and Biological Engineering and.
Julie A HoyFrom the Divisions of Biology and Biological Engineering and.
Dianne K NewmanFrom the Divisions of Biology and Biological Engineering and dkn@caltech.edu.
California Institute of Technology · US

Funding

Geobiological approaches to understanding pulmonary infections in situR01HL117328 · NHLBI · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI NEWMAN, DIANNE K · 2012 to 2016
$2.1M
NHLBI NIH HHS R01 HL117328
6 · The paper itself

Abstract

Phenazines are a class of redox-active molecules produced by diverse bacteria and archaea. Many of the biological functions of phenazines, such as mediating signaling, iron acquisition, and redox homeostasis, derive from their redox activity. Although prior studies have focused on extracellular phenazine oxidation by oxygen and iron, here we report a search for reductants and catalysts of intracellular phenazine reduction in

Indexed as

Bacterial ProteinsCatalysisCrystallography, X-RayDihydrolipoamide DehydrogenaseKetoglutarate Dehydrogenase ComplexNADOxidation-ReductionPhenazinesProtein ConformationPseudomonas aeruginosaPyocyaninePyruvate Dehydrogenase Complex1-phenazinecarboxylic acidBacterial ProteinsDihydrolipoamide DehydrogenaseKetoglutarate Dehydrogenase ComplexNADPhenazinesPyocyaninePyruvate Dehydrogenase Complexdihydrolipoamide dehydrogenaseenzyme kineticsmetabolismphenazinePseudomonas aeruginosa (P. aeruginosa)pyruvate dehydrogenase complex (PDC)X-ray crystallography

Identifiers

PMID28174304
PMCPMC5392700
OpenAlexW2587185925

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.