Evidence map›Paper›PMID 28174251›Full record

ArticleDevelopment (Cambridge, England)2017

A process engineering approach to increase organoid yield.

Natasha Arora, Jasmin Imran Alsous, Jacob W Guggenheim, Michael Mak, Jorge Munera, James M Wells, Roger D Kamm, H Harry Asada, Stanislav Y Shvartsman, Linda G Griffith

Open access · bronzeAbstract read
In one paragraph

Article in Development (Cambridge, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 64 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Potential Use of Organoids in Regenerative Medicine.Tissue engineering and regenerative medicine · 2024
    Review
  7. Cells · 2024
    Article
  8. Article
  9. Review
  10. Review
  11. Recent Advances in Generation of In Vitro Cardiac Organoids.International journal of molecular sciences · 2023
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Everything You Always Wanted to Know About Organoid-Based Models (and Never Dared to Ask).Cellular and molecular gastroenterology and hepatology · 2022
    Review
  19. Gastric Organoids: Progress and Remaining Challenges.Cellular and molecular gastroenterology and hepatology · 2022
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Natasha AroraDepartment of Biological Engineering, Massachusetts Institute of Technology, 77 Massachusetts Ave, Cambridge, MA 02139, USA.
Jasmin Imran AlsousDepartment of Chemical and Biological Engineering, Princeton University, Washington Road, Princeton, NJ 08540, USA.
Jacob W GuggenheimDepartment of Mechanical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Ave, Cambridge, MA 02139, USA.
Michael MakDepartment of Mechanical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Ave, Cambridge, MA 02139, USA.
Jorge MuneraDivision of Developmental Biology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA.
James M WellsDivision of Developmental Biology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA.
Roger D KammDepartment of Biological Engineering, Massachusetts Institute of Technology, 77 Massachusetts Ave, Cambridge, MA 02139, USA.
H Harry AsadaDepartment of Mechanical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Ave, Cambridge, MA 02139, USA.
Stanislav Y ShvartsmanDepartment of Chemical and Biological Engineering, Princeton University, Washington Road, Princeton, NJ 08540, USA.
Linda G GriffithDepartment of Biological Engineering, Massachusetts Institute of Technology, 77 Massachusetts Ave, Cambridge, MA 02139, USA griff@mit.edu.ORCID 0000-0002-1801-5548
Massachusetts Institute of Technology · USCincinnati Children's Hospital Medical Center · USPrinceton University · US

Funding

Project-3: Modeling EA/TEF in human organoidsP01HD093363 · NICHD · CINCINNATI CHILDRENS HOSP MED CTR · PI Wendy K Chung, Paul scot Kingma · 2017 to 2026
$16.2M
Dynamics of epithelial morphogenesisR01GM107103 · NIGMS · PRINCETON UNIVERSITY · PI SHVARTSMAN, STANISLAV Y. · 2014 to 2017
$1.2M
NICHD NIH HHS P01 HD093363NIGMS NIH HHS R01 GM107103
6 · The paper itself

Abstract

Temporal manipulation of the

Indexed as

Cell CountCells, CulturedCell SizeDigestive SystemFlow CytometryHumansOrganoidsSpheroids, CellularTissue EngineeringAggregatesIntestinalOrganoidsProcess engineeringSortingYield

Identifiers

PMID28174251
PMCPMC5358111
OpenAlexW2587737921

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.