ArticleDevelopment (Cambridge, England)2017
A novel floor plate boundary defined by adjacent En1 and Dbx1 microdomains distinguishes midbrain dopamine and hypothalamic neurons.
Article in Development (Cambridge, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
25 citing papers in PubMed, 36 citations in OpenAlex.
- Reassessing forebrain organization: recent evidence challenges the prosomere model.Current opinion in genetics & development · 2026Review
- Modulation of WNT and FGF18 enhances yield and subtype identity of hPSC-derived midbrain dopamine neurons.The Journal of clinical investigation · 2026Article
- Resolving forebrain developmental organisation by analysis of differential growth patterns.Nature communications · 2025Article
- Article
- Molecular and spatial transcriptomic classification of midbrain dopamine neurons and their alterations in a LRRK2bioRxiv : the preprint server for biology · 2024Article
- Conserved roles of engrailed: patterning tissues and specifying cell types.Development (Cambridge, England) · 2024Review
- Enhanced production of mesencephalic dopaminergic neurons from lineage-restricted human undifferentiated stem cells.Nature communications · 2023Article
- Human midbrain dopaminergic neuronal differentiation markers predict cell therapy outcomes in a Parkinson's disease model.The Journal of clinical investigation · 2022Article
- Optimizing maturity and dose of iPSC-derived dopamine progenitor cell therapy for Parkinson's disease.NPJ Regenerative medicine · 2022Article
- Identification of ASCL1 as a determinant for human iPSC-derived dopaminergic neurons.Scientific reports · 2021Article
- Epigenetic inactivation of the autophagy-lysosomal system in appendix in Parkinson's disease.Nature communications · 2021Article
- Biphasic Activation of WNT Signaling Facilitates the Derivation of Midbrain Dopamine Neurons from hESCs for Translational Use.Cell stem cell · 2021Article
- Tangential Intrahypothalamic Migration of the Mouse Ventral Premamillary Nucleus and Fgf8 Signaling.Frontiers in cell and developmental biology · 2021Article
- Altered baseline and amphetamine-mediated behavioral profiles in dopamine transporter Cre (DAT-Ires-Cre) mice compared to tyrosine hydroxylase Cre (TH-Cre) mice.Psychopharmacology · 2020Article
- PRISM: A Progenitor-Restricted Intersectional Fate Mapping Approach Redefines Forebrain Lineages.Developmental cell · 2020Article
- Review
- Molecular Regulation in Dopaminergic Neuron Development. Cues to Unveil Molecular Pathogenesis and Pharmacological Targets of Neurodegeneration.International journal of molecular sciences · 2020Review
- Article
- Classification of Midbrain Dopamine Neurons Using Single-Cell Gene Expression Profiling Approaches.Trends in neurosciences · 2020Review
- Pluripotent Stem Cell Therapies for Parkinson Disease: Present Challenges and Future Opportunities.Frontiers in cell and developmental biology · 2020Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The mesodiencephalic floor plate (mdFP) is the source of diverse neuron types. Yet, how this structure is compartmentalized has not been clearly elucidated. Here, we identify a novel boundary subdividing the mdFP into two microdomains, defined by engrailed 1 (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.