Evidence map›Paper›PMID 28174238›Full record

ArticleDevelopment (Cambridge, England)2017

Functional characterisation of

Claire S Simon, Damien J Downes, Matthew E Gosden, Jelena Telenius, Douglas R Higgs, Jim R Hughes, Ita Costello, Elizabeth K Bikoff, Elizabeth J Robertson

Open access · hybridAbstract read
In one paragraph

Article in Development (Cambridge, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 39 citations in OpenAlex.

  1. A degron-based approach to manipulate Eomes functions in the context of the developing mouse embryo.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  2. Article
  3. Article
  4. Review
  5. Organization of the Pluripotent Genome.Cold Spring Harbor perspectives in biology · 2021
    Review
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  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Claire S SimonThe Sir William Dunn School of Pathology, University of Oxford, Oxford OX1 3RE, UK.
Damien J DownesMRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DS, UK.
Matthew E GosdenMRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DS, UK.
Jelena TeleniusMRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DS, UK.
Douglas R HiggsMRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DS, UK.
Jim R HughesMRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DS, UK.
Ita CostelloThe Sir William Dunn School of Pathology, University of Oxford, Oxford OX1 3RE, UK.
Elizabeth K BikoffThe Sir William Dunn School of Pathology, University of Oxford, Oxford OX1 3RE, UK.
Elizabeth J RobertsonThe Sir William Dunn School of Pathology, University of Oxford, Oxford OX1 3RE, UK elizabeth.robertson@path.ox.ac.uk.ORCID 0000-0001-6562-0225
John Radcliffe Hospital · GBUniversity of Oxford · GB

Funding

Medical Research Council G1000801Medical Research Council MC_U137961144Medical Research Council MC_U137961145Medical Research Council MC_UU_00016/14Medical Research Council MC_UU_12009/15Medical Research Council MC_UU_12009/4Wellcome Trust 102811Wellcome Trust 106130Wellcome Trust 4050189188
6 · The paper itself

Abstract

The T-box transcription factor (TF) Eomes is a key regulator of cell fate decisions during early mouse development. The

Indexed as

Gene Expression Regulation, DevelopmentalAnimalsCell DifferentiationChromatinEmbryo, MammalianEndodermEnhancer Elements, GeneticFemaleForkhead Transcription FactorsGastrulationGene DeletionGenes, ReporterGene TargetingGenotypeMice, Inbred C57BLModels, BiologicalChromatinEomes protein, mouseForkhead Transcription FactorsFoxh1 protein, mousePolycomb-Group ProteinsSmad2 ProteinT-Box Domain ProteinsCapture-CDefinitive endodermEnhancerEomesoderminNodal signalling

Identifiers

PMID28174238
PMCPMC5399628
OpenAlexW2587504663

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.