Evidence map›Paper›PMID 28174214›Full record

ArticleJournal of lipid research2017

Excitotoxicity-induced prostaglandin D

Kensuke Iwasa, Shinji Yamamoto, Sosuke Yagishita, Kei Maruyama, Keisuke Yoshikawa

Open access · hybridAbstract read
In one paragraph

Article in Journal of lipid research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Therapeutic implications of cyclooxygenase (COX) inhibitors in ischemic injury.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2022
    Pooled it
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  9. Systemic delivery of antagomirs during blood-brain barrier disruption is disease-modifying in experimental epilepsy.Molecular therapy : the journal of the American Society of Gene Therapy · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Kensuke IwasaDepartment of Pharmacology, Faculty of Medicine, Saitama Medical University, Iruma-gun, Saitama, Japan.
Shinji YamamotoDepartment of Pharmacology, Faculty of Medicine, Saitama Medical University, Iruma-gun, Saitama, Japan.
Sosuke YagishitaDepartment of Pharmacology, Faculty of Medicine, Saitama Medical University, Iruma-gun, Saitama, Japan.
Kei MaruyamaDepartment of Pharmacology, Faculty of Medicine, Saitama Medical University, Iruma-gun, Saitama, Japan.
Keisuke YoshikawaDepartment of Pharmacology, Faculty of Medicine, Saitama Medical University, Iruma-gun, Saitama, Japan. Electronic address: keisukey@saitama-med.ac.jp.
Saitama Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Excitotoxicity is the pivotal mechanism of neuronal death. Prostaglandins (PGs) produced during excitotoxicity play important roles in neurodegenerative conditions. Previously, we demonstrated that initial burst productions of PGD

Indexed as

AnimalsCell DeathCyclooxygenase 2HippocampusKainic AcidMicrogliaNeuronsNitrobenzenesProstaglandin D2RatsSulfonamidesCyclooxygenase 2Kainic AcidN-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamideNitrobenzenesProstaglandin D2Sulfonamideskainic acidmicroglianeurons

Identifiers

PMID28174214
PMCPMC5392741
OpenAlexW2587537088

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.