Evidence map›Paper›PMID 28174205›Full record

ArticleThe Journal of cell biology2017

The VDAC2-BAK axis regulates peroxisomal membrane permeability.

Ken-Ichiro Hosoi, Non Miyata, Satoru Mukai, Satomi Furuki, Kanji Okumoto, Emily H Cheng, Yukio Fujiki

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of cell biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 66 citations in OpenAlex.

  1. Mitochondria and cell death.Nature cell biology · 2024
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Lysosomal KEMBO reports · 2022
    Article
  8. Article
  9. Article
  10. Control of mitochondrial dynamics and apoptotic pathways by peroxisomes.Frontiers in cell and developmental biology · 2022
    Review
  11. Article
  12. Review
  13. VPS13D promotes peroxisome biogenesis.The Journal of cell biology · 2021
    Article
  14. The peroxisomal enzyme, FAR1, is induced during ER stress in an ATF6-dependent manner in cardiac myocytes.American journal of physiology. Heart and circulatory physiology · 2021
    Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Ken-Ichiro HosoiDepartment of Biology, Faculty of Sciences, Kyushu University, Nishi-ku, Fukuoka 819-0395, Japan.
Non MiyataDepartment of Biology, Faculty of Sciences, Kyushu University, Nishi-ku, Fukuoka 819-0395, Japan.ORCID 0000-0002-5945-909X
Satoru MukaiDepartment of Biology, Faculty of Sciences, Kyushu University, Nishi-ku, Fukuoka 819-0395, Japan.
Satomi FurukiDepartment of Biology, Faculty of Sciences, Kyushu University, Nishi-ku, Fukuoka 819-0395, Japan.
Kanji OkumotoDepartment of Biology, Faculty of Sciences, Kyushu University, Nishi-ku, Fukuoka 819-0395, Japan.
Emily H ChengHuman Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065.
Yukio FujikiMedical Institute of Bioregulation, Kyushu University, Higashi-ku, Fukuoka 812-8582, Japan yfujiki@kyudai.jp.ORCID 0000-0002-8138-6376
Kyushu University · JPMemorial Sloan Kettering Cancer Center · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
Apoptotic Network Integrated at the MitochondrionR01CA125562 · NCI · WASHINGTON UNIVERSITY · PI CHENG, EMILY H · 2007 to 2020
$3.4M
NCI NIH HHS P30 CA008748NCI NIH HHS R01 CA125562
6 · The paper itself

Abstract

Peroxisomal biogenesis disorders (PBDs) are fatal genetic diseases consisting of 14 complementation groups (CGs). We previously isolated a peroxisome-deficient Chinese hamster ovary cell mutant, ZP114, which belongs to none of these CGs. Using a functional screening strategy, VDAC2 was identified as rescuing the peroxisomal deficiency of ZP114 where VDAC2 expression was not detected. Interestingly, knockdown of

Indexed as

Animalsbcl-2-Associated X Proteinbcl-2 Homologous Antagonist-Killer ProteinCell LineCell Membrane PermeabilityCHO CellsCricetinaeCricetulusCytosolMembrane ProteinsMitochondriaPeroxisomal DisordersPeroxisomesVoltage-Dependent Anion Channel 2bcl-2-Associated X Proteinbcl-2 Homologous Antagonist-Killer ProteinMembrane ProteinsVoltage-Dependent Anion Channel 2

Identifiers

PMID28174205
PMCPMC5350511
OpenAlexW2586104162

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.