Evidence map›Paper›PMID 28174171›Full record

ReviewJournal of the American Heart Association2017

Indoxyl Sulfate: A Novel Cardiovascular Risk Factor in Chronic Kidney Disease.

Szu-Chun Hung, Ko-Lin Kuo, Chih-Cheng Wu, Der-Cherng Tarng

2 registry-linked trialsAbstract readReview
In one paragraph

Review in Journal of the American Heart Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 142 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
142citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04554498 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Toxins Removal and Inflammatory State modulAtion During Online Hemodiafiltration: Comparison of Two Different Dialyzers

TypeinterventionalSponsorIRCCS Azienda Ospedaliero-Universitaria di BolognaRan2022 to 2024Enrolled16ConditionsHemodialysis Complication, Inflammation, Uremic, ToxemiaArms1) high flux hemodiafiltration thrice -weekly during a 24 month follow-up
NCT06877585 completednot on this mapstarted 2025, after this paper: background citation

Association Between Fecal Microbiota Composition, Metabolite Concentrations, and Indoxyl Sulfate Levels in Hemodialysis Patients

Typeobservational_patient_registrySponsorTungs' Taichung Metroharbour HospitalRan2025 to 2025Enrolled58ConditionsDysbiosis
3 · Its place in the literature

Who cites it

142 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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  16. Urinary biomarkers of diabetic kidney disease.World journal of diabetes · 2026
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82 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Szu-Chun HungDivision of Nephrology, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.
Ko-Lin KuoDivision of Nephrology, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.
Chih-Cheng WuCardiovascular Center, National Taiwan University Hospital, Hsinchu Branch, Hsinchu, Taiwan.
Der-Cherng TarngInstitutes of Physiology and Clinical Medicine, National Yang-Ming University, Taipei, Taiwan dctarng@vghtpe.gov.tw.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cardiovascular DiseasesRenal Insufficiency, ChronicBiomarkersHumansIndicanRisk FactorsBiomarkersIndicancardiovascular diseasechronic kidney diseasegut microbiotaindoxyl sulfateuremic toxin

Identifiers

PMID28174171
PMCPMC5523780

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.