ReviewBMC nephrology2017
"Bowel prep hyponatremia" - a state of acute water intoxication facilitated by low dietary solute intake: case report and literature review.
Review in BMC nephrology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
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Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- Pooled it
- Clinical characteristics and outcomes of hyponatraemia associated with oral water intake in adults: a systematic review.BMJ open · 2021Pooled it
- Managing hyponatremia: fast or slow? Why, when, how, and controversies.Clinical kidney journal · 2026Review
- A case of impaired consciousness due to water intoxication during underwater endoscopic submucosal dissection for colorectal cancer.Clinical journal of gastroenterology · 2026Article
- Recurrent Severe Hyponatremia Following Polyethylene Glycol Electrolyte Lavage Solution with Ascorbic Acid in a Patient with Undiagnosed Syndrome of Inappropriate Antidiuretic Hormone Secretion.The American journal of case reports · 2025Article
- Article
- Syndrome of Inappropriate Antidiuresis.Journal of the American Society of Nephrology : JASN · 2025Review
- Article
- Article
- [Consensus recommendations on the diagnosis and treatment of hyponatremia from the Austrian Society for Nephrology 2024].Wiener klinische Wochenschrift · 2024Article
- A case of severe acute hyponatremia after colonoscopy with polyethylene glycol plus ascorbic acid bowel preparation.CEN case reports · 2023Article
- Hyponatremic encephalopathy due to polyethylene glycol-based bowel preparation for colonoscopy: A case report.World journal of clinical cases · 2023Article
- Seizure from water intoxication following bowel preparation: a case report.BMC nephrology · 2022Article
- Serum electrolytes, osmolality, and cleansing quality after bowel prep for colonoscopy with a PEG solution containing ascorbic acid and electrolytes.International journal of colorectal disease · 2022Article
- Symptomatic Hyponatremia following Bowel Preparation for Colonoscopy: A Case Report.JNMA; journal of the Nepal Medical Association · 2020Article
- Severe symptomatic hyponatraemia secondary to bowel preparation.BMJ case reports · 2019Article
- Hyponatremic Coma after Bowel Preparation.European journal of case reports in internal medicine · 2019Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSymptomatic hyponatremia is considered a rare complication of oral bowel preparation for colonoscopy. The pathophysiology underlying this phenomenon has been widely regarded as a mere sequela of excessive arginine vasopressin (AVP) release. CASE PRESENTATION: This case describes a 61-year old woman who developed acute hyponatremic encephalopathy when preparing for elective outpatient lower endoscopy. She had had negligible oral solute intake for two days and ingested four liters of clear fluid within two hours. On admission, the patient was agitated and had slurred speech. Treatment with hypertonic saline lead to full recovery. A brisk aquaresis confirmed acute dilutional hyponatremia.
conclusionApart from elevated AVP-levels, the amount and speed of fluid intake and concomitant low-solute intake constitute important risk factors in the development of clinically relevant hyponatremias in patients undergoing colonoscopies. Understanding that the cause of sodium imbalance in this scenario is multifactorial and complex is pivotal to recognizing and ideally preventing this complication, for which we propose the term "bowel prep hyponatremia".
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