ArticleBMC evolutionary biology2017
Origin and diversification of leucine-rich repeat receptor-like protein kinase (LRR-RLK) genes in plants.
Article in BMC evolutionary biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 116 papers.
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116 citing papers in PubMed, 218 citations in OpenAlex.
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- Comparative analysis of PRR receptors and R genes reveals structural and functional divergence between wild, ancestral, and commercial citrus species.BMC genomics · 2026Article
- Genome-wide identification and expression analysis of salt-responsive bHLH transcription factors in the wheat (Frontiers in plant science · 2026Article
- The receptor-like kinase SlLRR-RLK94 as a positive regulator of tomato resistance to Phytophthora infestans.Plant cell reports · 2025Article
- Proteomics Integrated with Transcriptomics of Clubroot Resistant and SusceptibleInternational journal of molecular sciences · 2025Article
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- A novel trait to reduce the mechanical damage of peach fruits at harvest: The first genetic dissection study for peduncle length.Molecular breeding : new strategies in plant improvement · 2025Article
- LRR-RLK subfamily II of coreceptors: emerging, non-canonical and canonical roles in plant antiviral immunity and development.Frontiers in plant science · 2025Review
- Epitranscriptomic and expression profiling inComputational and structural biotechnology journal · 2025Article
- Genome-wide identification and expression analyses of theFrontiers in plant science · 2025Article
- A novel LRR receptor-like kinase BRAK reciprocally phosphorylates PSKR1 to enhance growth and defense in tomato.The EMBO journal · 2024Article
- Plant Pattern recognition receptors: Exploring their evolution, diversification, and spatiotemporal regulation.Current opinion in plant biology · 2024Article
- An island of receptor-like genes at the Rrs13 locus on barley chromosome 6HS co-locate with three novel sources of scald resistance.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Article
- Transcriptome-wide Identification of Nine Tandem Repeat Protein Families in Roselle (Tropical life sciences research · 2024Article
- Genomic Survey of LRR-RLK Genes inPlants (Basel, Switzerland) · 2024Article
56 more citing papers are in PubMed but not listed here.
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLeucine-rich repeat receptor-like protein kinases (LRR-RLKs) are the largest group of receptor-like kinases in plants and play crucial roles in development and stress responses. The evolutionary relationships among LRR-RLK genes have been investigated in flowering plants; however, no comprehensive studies have been performed for these genes in more ancestral groups. The subfamily classification of LRR-RLK genes in plants, the evolutionary history and driving force for the evolution of each LRR-RLK subfamily remain to be understood.
resultsWe identified 119 LRR-RLK genes in the Physcomitrella patens moss genome, 67 LRR-RLK genes in the Selaginella moellendorffii lycophyte genome, and no LRR-RLK genes in five green algae genomes. Furthermore, these LRR-RLK sequences, along with previously reported LRR-RLK sequences from Arabidopsis thaliana and Oryza sativa, were subjected to evolutionary analyses. Phylogenetic analyses revealed that plant LRR-RLKs belong to 19 subfamilies, eighteen of which were established in early land plants, and one of which evolved in flowering plants. More importantly, we found that the basic structures of LRR-RLK genes for most subfamilies are established in early land plants and conserved within subfamilies and across different plant lineages, but divergent among subfamilies. In addition, most members of the same subfamily had common protein motif compositions, whereas members of different subfamilies showed variations in protein motif compositions. The unique gene structure and protein motif compositions of each subfamily differentiate the subfamily classifications and, more importantly, provide evidence for functional divergence among LRR-RLK subfamilies. Maximum likelihood analyses showed that some sites within four subfamilies were under positive selection.
conclusionsMuch of the diversity of plant LRR-RLK genes was established in early land plants. Positive selection contributed to the evolution of a few LRR-RLK subfamilies.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.