Evidence map›Paper›PMID 28173641›Full record

ArticleBiomolecules & therapeutics2017

Effects of Adamantyl Derivatives on Pharmacokinetic Behavior of Paclitaxel in Rats.

Kyung Mi Kim, Kyeong Lee, Kyusic Jang, Yae Seul Moon, Hwa Jeong Lee, Sandy Jeong Rhie

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecules & therapeutics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Kyung Mi KimGraduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul 03760, Republic of Korea.
Kyeong LeeCollege of Pharmacy, Dongguk University, Goyang 10326, Republic of Korea.
Kyusic JangCollege of Pharmacy, Dongguk University, Goyang 10326, Republic of Korea.
Yae Seul MoonGraduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul 03760, Republic of Korea.
Hwa Jeong LeeGraduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul 03760, Republic of Korea.
Sandy Jeong RhieCollege of Pharmacy and Division of Life and Pharmaceutical Sciences, Ewha Womans University, Seoul 03760, Republic of Korea.
Ewha Womans University · KRDongguk University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Paclitaxel (PTX) is one of the most frequently used anticancer agent for treating refractory ovarian cancer, metastatic breast cancer and non-small cell lung cancer. However, its oral administration is impeded by very low bioavailability (<5%) due to the P-glycopprotein (P-gp) efflux pump effect. This study investigated

Indexed as

Adamantyl derivativesOral bioavailabilityPaclitaxelP-glycoproteinVerapamil

Identifiers

PMID28173641
PMCPMC5590800
OpenAlexW2587438431

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.