Evidence map›Paper›PMID 28173640›Full record

ArticleBiomolecules & therapeutics2017

Tanshinone IIA Protects Endothelial Cells from H₂O₂-Induced Injuries via PXR Activation.

Haiyan Zhu, Zhiwu Chen, Zengchun Ma, Hongling Tan, Chengrong Xiao, Xianglin Tang, Boli Zhang, Yuguang Wang, Yue Gao

Erratum issuedAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecules & therapeutics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
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  6. Review
  7. Frontiers in pharmacology · 2022
    Article
  8. Article
  9. Review
  10. Review
  11. PXR: a center of transcriptional regulation in cancer.Acta pharmaceutica Sinica. B · 2020
    Review
  12. Article
  13. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Haiyan ZhuDepartment of Pharmacology, Anhui Medical University, Hefei 230032, China.
Zhiwu ChenDepartment of Pharmacology, Anhui Medical University, Hefei 230032, China.
Zengchun MaDepartment of Pharmacology and Toxicology, Beijing Institute of Radiation Medicine, Beijing 100850, China.
Hongling TanDepartment of Pharmacology and Toxicology, Beijing Institute of Radiation Medicine, Beijing 100850, China.
Chengrong XiaoDepartment of Pharmacology and Toxicology, Beijing Institute of Radiation Medicine, Beijing 100850, China.
Xianglin TangDepartment of Pharmacology and Toxicology, Beijing Institute of Radiation Medicine, Beijing 100850, China.
Boli ZhangTianjin University of Traditional Chinese Medicine, Tianjin 300193, China.
Yuguang WangDepartment of Pharmacology, Anhui Medical University, Hefei 230032, China.
Yue GaoDepartment of Pharmacology, Anhui Medical University, Hefei 230032, China.
Anhui Medical University · CNBeijing Radiation Center · CNTianjin University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tanshinone IIA (Tan IIA) is a pharmacologically active substance extracted from the rhizome of

Indexed as

ApoptosisHUVECsInflammationOxidative stressPXRTanshinone IIA

Identifiers

PMID28173640
PMCPMC5685429
OpenAlexW2587397794

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.