Evidence map›Paper›PMID 28172581›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2017

First Occurrence of Diabetes, Chronic Kidney Disease, and Hypertension Among North American HIV-Infected Adults, 2000-2013.

Cherise Wong, Stephen J Gange, Kate Buchacz, Richard D Moore, Amy C Justice, Michael A Horberg, M John Gill, John R Koethe, Peter F Rebeiro, Michael J Silverberg and 13 more

Open access · bronzeAbstract readHistorical Article
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 3 pooled it
8.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 3 syntheses or guidelines pooled it, 73 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Guideline
  4. Trial
  5. Trial
  6. Article
  7. Article
  8. Changes in the Prevalence of Non-AIDS Conditions Among Hospitalized Persons With HIV in the United States and Canada, 2008-2018.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Updates on HIV and Kidney Disease.Current HIV/AIDS reports · 2023
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 11 institutions in 3 countries.

Cherise WongJohns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.
Stephen J GangeJohns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.
Kate BuchaczCenters for Disease Control and Prevention, Atlanta, Georgia.
Richard D MooreJohns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.
Amy C JusticeVeterans Affairs Connecticut Healthcare System, West Haven.
Michael A HorbergMid-Atlantic Permanente Research Institute, Kaiser Permanente Mid-Atlantic States, Rockville, Maryland.
M John GillUniversity of Calgary, Alberta, Canada.
John R KoetheVanderbilt University, Nashville, Tennessee.
Peter F RebeiroVanderbilt University, Nashville, Tennessee.
Michael J SilverbergKaiser Permanente Division of Research, Kaiser Permanente Northern California, Oakland.
Frank J PalellaNorthwestern University, Chicago, Illinois.
Pragna PatelCenters for Disease Control and Prevention, Atlanta, Georgia.
Mari M KitahataUniversity of Washington, Seattle.
Heidi M CraneUniversity of Washington, Seattle.
Alison G AbrahamJohns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.
Hasina SamjiBritish Columbia Centre for Excellence in HIV/AIDS, Vancouver, Canada.
Sonia NapravnikUniversity of North Carolina at Chapel Hill.
Tareq AhmedBritish Columbia Centre for Excellence in HIV/AIDS, Vancouver, Canada.
Jennifer E ThorneJohns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.
Ronald J BoschHarvard School of Public Health, Boston, Massachusetts.
Angel M MayorUniversidad Central del Caribe, Bayamon, Puerto Rico.
Keri N AlthoffJohns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.
North American AIDS Cohort Collaboration on Research and Design (NA-ACCORD)
Johns Hopkins University · USAIDS Vancouver · CACenters for Disease Control and Prevention · USKaiser Permanente · USUniversity of Washington · USVanderbilt University · USCentral University of the Caribbean · PRNorthwestern University · USUniversity of Calgary · CAUniversity of North Carolina at Chapel Hill · USVA Connecticut Healthcare System · US

Funding

Statistical and Data Management Center (SDMC), AIDS Clinical Trials Group (ACTG)UM1AI068634 · NIAID · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI Marlene Ann Cooper, Michael David Hughes · 2011 to 2026
$246.6M
Virology, Immunology, and Microbiology CoreP30AI050410 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVID M. MARGOLIS · 2001 to 2026
$76.9M
MULTICENTER AIDS COHORT STUDYU01AI035039 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI WOLINSKY, STEVEN M · 1993 to 2018
$66.4M
North American AIDS Cohorts on Collaboration and Design (NAACCORD)U01AI069918 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Keri Nicole Althoff, RICHARD Douglas MOORE · 2006 to 2026
$65.2M
The Silver Tsunami: Projecting multimorbidity, polypharmacy,and healthcare costs for those aging with HIV in the USR01AG053100 · NIA · JOHNS HOPKINS UNIVERSITY · PI ALTHOFF, KERI NICOLE · 2016 to 2020
$2.7M
Antiretroviral Therapy Strategies to Lower Cancer Risk in HIV-Infected PersonsR01CA165937 · NCI · KAISER FOUNDATION RESEARCH INSTITUTE · PI DUBROW, ROBERT D, SILVERBERG, MICHAEL J · 2012 to 2015
$2.4M
Challenging and Expanding Paradigms of Aging with HIVK01AI093197 · NIAID · JOHNS HOPKINS UNIVERSITY · PI ALTHOFF, KERI NICOLE · 2011 to 2015
$646k
NCI NIH HHS R01 CA165937NIAID NIH HHS K01 AI093197NIAID NIH HHS P30 AI050410NIAID NIH HHS U01 AI035039NIAID NIH HHS U01 AI069918NIAID NIH HHS UM1 AI068634NIA NIH HHS R01 AG053100
6 · The paper itself

Abstract

Background: There remains concern regarding the occurrence of noncommunicable diseases (NCDs) among individuals aging with human immunodeficiency virus (HIV), but few studies have described whether disparities between demographic subgroups are present among individuals on antiretroviral therapy (ART) with access to care. Methods: We assessed the first documented occurrence of type 2 diabetes mellitus (DM), chronic kidney disease (CKD), and treated hypertension (HTN) by age, sex, and race within the North American AIDS Cohort Collaboration on Research and Design (NA-ACCORD). HIV-infected adults (≥18 years) who initiated ART were observed for first NCD occurrence between 1 January 2000 and 31 December 2013. Cumulative incidences as of age 70 were estimated accounting for the competing risk of death; Poisson regression was used to compare rates of NCD occurrence by demographic subgroup. Results: We included >50000 persons with >250000 person-years of follow-up. Median follow-up was 4.7 (interquartile range, 2.4–8.1) years. Rates of first occurrence (per 100 person-years) were 1.2 for DM, 0.6 for CKD, and 2.6 for HTN. Relative to non-black women, the cumulative incidences were increased in black women (68% vs 51% for HTN, 52% vs 41% for DM, and 38% vs 35% for CKD; all P < .001); this disparity was also found among men (73% vs 60% for HTN, 44% vs 34% for DM, and 30% vs 25% for CKD; all P < .001). Conclusions: Racial disparities in the occurrence of DM, CKD, and HTN emphasize the need for prevention and treatment options for these HIV populations receiving care in North America.

Indexed as

AdultAgedAntiretroviral Therapy, Highly ActiveDiabetes Mellitus, Type 2FemaleHistory, 21st CenturyHIV InfectionsHumansHypertensionMaleMiddle AgedNorth AmericaPatient Outcome AssessmentPopulation SurveillanceRenal Insufficiency, ChronicRisk Factors

Identifiers

PMID28172581
PMCPMC5850614
OpenAlexW2560846244

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.