Evidence map›Paper›PMID 28172500›Full record

ArticleCardiovascular research2016

Sema6D acts downstream of bone morphogenetic protein signalling to promote atrioventricular cushion development in mice.

Yin Peng, Lanying Song, Ding Li, Robert Kesterson, Jianbo Wang, Lizhong Wang, Gregg Rokosh, Bingruo Wu, Qin Wang, Kai Jiao

Abstract read
In one paragraph

Article in Cardiovascular research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Plexin-A1 expression in the inhibitory neurons of infralimbic cortex regulates the specificity of fear memory in male mice.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022
    Article
  11. Article
  12. Frontiers in molecular neuroscience · 2022
    Article
  13. CHD7 regulates cardiovascular development through ATP-dependent and -independent activities.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  14. Article
  15. Article
  16. Article
  17. Primary cilia defects causing mitral valve prolapse.Science translational medicine · 2019
    Article
  18. Role of Semaphorin Signaling During Cardiovascular Development.Journal of the American Heart Association · 2018
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yin PengDepartment of Genetics, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Lanying SongDepartment of Genetics, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Ding LiDepartment of Cell, Developmental and Integrative Biology, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Robert KestersonDepartment of Genetics, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Jianbo WangDepartment of Cell, Developmental and Integrative Biology, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Lizhong WangDepartment of Genetics, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Gregg RokoshDivision of Cardiovascular Disease, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Bingruo WuDepartment of Genetics, Albert Einstein College of Medicine, New York, NY 10461, USA.
Qin WangDepartment of Cell, Developmental and Integrative Biology, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Kai JiaoDepartment of Genetics, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.

Funding

XRAY CRYSTALLOGRAPHYP30CA013148 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Robert S Welner · 1985 to 2026
$165.9M
Research Training & Career Development ProgramU54CA118638 · NCI · MOREHOUSE SCHOOL OF MEDICINE · PI Brian M. Rivers · 2005 to 2026
$22.7M
Research Education CoreU54CA118623 · NCI · TUSKEGEE UNIVERSITY · PI STEPHEN O SODEKE · 2005 to 2026
$20.2M
INFRASTRUCTURE IIG12MD007585 · NIMHD · TUSKEGEE UNIVERSITY · PI YATES, CLAYTON · 2012 to 2016
$4.6M
The Roles of Semaphorin Signaling During Valvuloseptal DevelopmentR01HL095783 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI JIAO, KAI · 2010 to 2021
$3.4M
Planar cell polarity signaling in second heart field developmentR01HL109130 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI WANG, JIANBO · 2011 to 2015
$1.8M
Molecular mechanisms regulating mouse valvulogenesisR03HD082634 · NICHD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI JIAO, KAI · 2014 to 2015
$145k
NCI NIH HHS P30 CA013148NCI NIH HHS U54 CA118623NCI NIH HHS U54 CA118638NHLBI NIH HHS R01 HL095783NHLBI NIH HHS R01 HL109130NICHD NIH HHS R03 HD082634NIMHD NIH HHS G12 MD007585
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsAtrioventricular NodeBone Morphogenetic ProteinsCell MovementEpithelial-Mesenchymal TransitionMesodermMiceMice, Inbred C57BLrho GTP-Binding ProteinsSemaphorinsSignal TransductionBone Morphogenetic Proteinsrho GTP-Binding ProteinsSema6d protein, mouseSemaphorins

Identifiers

PMID28172500
PMCPMC5901116

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.