Evidence map›Paper›PMID 28171746›Full record

ReviewDevelopmental cell2017

Macrophage Functions in Tissue Patterning and Disease: New Insights from the Fly.

Will Wood, Paul Martin

Abstract readReview
In one paragraph

Review in Developmental cell, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Exploring new dimensions of immune cell biology inbioRxiv : the preprint server for biology · 2024
    Article
  10. Article
  11. Article
  12. The macrophage genetic cassetteScience advances · 2023
    Article
  13. Nonpathological inflammation drives the development of an avian flight adaptation.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  14. Macrophage subpopulation identity inFrontiers in immunology · 2023
    Article
  15. Hematopoietic Stem Cell Development in Mammalian Embryos.Advances in experimental medicine and biology · 2023
    Review
  16. Article
  17. Wound Healing Insights from Flies and Fish.Cold Spring Harbor perspectives in biology · 2022
    Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Will WoodDepartment of Cellular and Molecular Medicine, Biomedical Sciences, University of Bristol, Bristol BS8 1TD, UK. Electronic address: w.wood@bristol.ac.uk.
Paul MartinDepartments of Biochemistry and Physiology, Pharmacology and Neuroscience, Biomedical Sciences, University of Bristol, Bristol BS8 1TD, UK; School of Medicine, Cardiff University, Cardiff CF14 4XN, UK; Lee Kong Chiang School of Medicine, Nanyang Technological University, Singapore 636921, Singapore. Electronic address: paul.martin@bristol.ac.uk.

Funding

Medical Research Council MR/J002577/1Wellcome Trust 097791/Z/11/ZWellcome Trust 107940/Z/15/Z
6 · The paper itself

Abstract

Macrophages are multifunctional innate immune cells that seed all tissues within the body and play disparate roles throughout development and in adult tissues, both in health and disease. Their complex developmental origins and many of their functions are being deciphered in mammalian tissues, but opportunities for live imaging and the genetic tractability of Drosophila are offering complementary insights into how these fascinating cells integrate a multitude of guidance cues to fulfill their many tasks and migrate to distant sites to either direct developmental patterning or raise an inflammatory response.

Indexed as

Body PatterningDiseaseAnimalsCell LineageDrosophila melanogasterHumansMacrophagesSignal TransductionapoptosisdevelopmentdiseaseDrosophilaimmunityinflammationmacrophagemigrationwound

Identifiers

PMID28171746
PMCPMC5300050

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.