Equipoise in Research: Integrating Ethics and Science in Human Research.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

1. Inoperable malignant bowel obstruction: palliative interventions outcomes - mixed-methods systematic review.BMJ supportive & palliative care · 2024
   Pooled it
2. Bayes and the Evidence Base: Reanalyzing Trials Using Many Priors Does Not Contribute to Consensus.American journal of respiratory and critical care medicine · 2024
   Article
3. Is equipoise a useful concept to justify randomised controlled trials in the cultural context of Pakistan? A survey of clinicians in relation to a trial of talking therapy for young people who self-harm.Trials · 2023
   Article
4. What do we talk about when we talk about "equipoise"? Stakeholder interviews assessing the use of equipoise in clinical research ethics.Trials · 2023
   Review
5. Reframing the perception of outliers and negative data in translational research.Brain research bulletin · 2023
   Review
6. Rethinking Benefits in Health Research, Reflections of an Ethics Committee.The Yale journal of biology and medicine · 2022
   Review
7. Cross-roads for meta-analysis and network meta-analysis ofGut · 2022
   Review
8. Analyses of the Rationale and Implementation of Research Biopsies in Oncology Clinical Trials at a Tertiary Cancer Center.The oncologist · 2021
   Article
9. Current COVID-19 vaccine trials in high-income countries: are placebo-controlled trials ethical?Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2021
   Article
10. An iterative, interdisciplinary, collaborative framework for developing and evaluating digital behavior change interventions.Translational behavioral medicine · 2020
    Article
11. Preserving equipoise and performing randomised trials for COVID-19 social distancing interventions.Epidemiology and psychiatric sciences · 2020
    Article
12. Communicative challenges among physicians, patients, and family caregivers in cancer care: An exploratory qualitative study in Ethiopia.PloS one · 2020
    Article
13. Comparing Transbronchial Cryobiopsy and Surgical Biopsy in Idiopathic Pulmonary Fibrosis.American journal of respiratory and critical care medicine · 2019
    Article
14. Support of New Triage Protocol among Acute Stroke Care Providers.Interventional neurology · 2018
    Article
15. Primary outcome switching among drug trials with and without principal investigator financial ties to industry: a cross-sectional study.BMJ open · 2018
    Article
16. Prostate cancer screening: what can we learn from randomised trials?Translational andrology and urology · 2018
    Review
17. The NSIGHT1-randomized controlled trial: rapid whole-genome sequencing for accelerated etiologic diagnosis in critically ill infants.NPJ genomic medicine · 2018
    Article
18. Challenges in conducting clinical nutrition research.Nutrition reviews · 2017
    Review
19. Pushing the Boundaries of Psychiatric Neuroimaging to Ground Diagnosis in Biology.eNeuro
    Review

Corrections and comments

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Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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