ArticlePediatric research2017
Early growth faltering in post-institutionalized youth and later anthropometric and pubertal development.
Article in Pediatric research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.
- Parent-child separation and cardiometabolic outcomes and risk factors in adulthood: A systematic review.Psychoneuroendocrinology · 2023Pooled it
- Biological aging in childhood and adolescence following experiences of threat and deprivation: A systematic review and meta-analysis.Psychological bulletin · 2020Pooled it
- The Consequences of Foster Care Versus Institutional Care in Early Childhood on Adolescent Cardiometabolic and Immune Markers: Results From a Randomized Controlled Trial.Psychosomatic medicine · 2019Trial
- Caregiving Disruptions Affect Growth and Pubertal Development in Early Adolescence in Institutionalized and Fostered Romanian Children: A Randomized Clinical Trial.The Journal of pediatrics · 2018Trial
- The decline in the physical stature of the U.S. population parallels the diminution in the rate of increase in life expectancy.SSM - population health · 2025Article
- Post-adoption experiences of discrimination moderated by sleep quality are associated with depressive symptoms in previously institutionalized youth over and above deprivation-induced depression risk.Development and psychopathology · 2024Article
- Exploring sex differences in trajectories of pubertal development and mental health following early adversity.Psychoneuroendocrinology · 2024Article
- Mothers' prenatal distress accelerates adrenal pubertal development in daughters.Psychoneuroendocrinology · 2024Article
- Pubertal timing, sex hormone levels, and associations between early life adversity and accelerated development amongst 11-year-old children of parents with schizophrenia or bipolar disorder and controls: The Danish high risk and Resilience study via 11.Comprehensive psychoneuroendocrinology · 2023Article
- Prevention of Epithelial Ovarian Cancer.Cold Spring Harbor perspectives in medicine · 2023Review
- Early-life stress and current stress predict BMI and height growth trajectories in puberty.Developmental psychobiology · 2022Article
- What was learned from studying the effects of early institutional deprivation.Pharmacology, biochemistry, and behavior · 2021Review
- Pubertal transition with current life stress and support alters longitudinal diurnal cortisol patterns in adolescents exposed to early life adversity.Developmental psychobiology · 2021Article
- Pubertal recalibration of cortisol-DHEA coupling in previously-institutionalized children.Hormones and behavior · 2020Article
- Auxological and endocrinological features in internationally adopted children.Italian journal of pediatrics · 2020Review
- Pubertal development mediates the association between family environment and brain structure and function in childhood.Development and psychopathology · 2020Article
- Synthesizing Views to Understand Sex Differences in Response to Early Life Adversity.Trends in neurosciences · 2020Review
- Earlier age at menarche as a transdiagnostic mechanism linking childhood trauma with multiple forms of psychopathology in adolescent girls.Psychological medicine · 2020Article
- Pubertal stress recalibration reverses the effects of early life stress in postinstitutionalized children.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Auxo-endocrinological features in a cohort of internationally adopted children in Italy.World journal of pediatrics : WJP · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
BackgroundEarly-life adversity that increases the risk of growth stunting is hypothesized to increase the risk of obesity and, in girls, early-onset puberty. This hypothesis was tested in children adopted from orphanages.MethodsPost-institutionalized (PI) youth were compared with youth reared in comparable families (non-adopted; NA) on height, weight, pubertal stage, and fat mass (127 PI, 80 female; 156 NA, 85 female, aged 7-14 years). Anthropometric findings at adoption were obtained from first US clinic visits.ResultsOverall, 25% of PI youth were height-stunted (<3rd percentile) at adoption. Years post adoption, PI youth had lower BMI-for-age (P=0.004), height-for-age (P<0.001), and less body fat (P<0.001) than NA youth had, but they did not differ by sex. Pubertal status did not differ by group or sex. The anthropometric findings held when the stunted-at-adoption subset was examined; they were also less likely to be in central puberty than other PI youth.ConclusionEarly deprived orphanage care increases the risk of growth stunting but not obesity in children adopted into US families, and it does not independently contribute to early-onset puberty for PI girls. The role of the environment following early adversity may modify the impact of early adverse care.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.