ArticlePediatric research2017
Peripubertal dietary flavonol and lignan intake and age at menarche in a longitudinal cohort of girls.
Article in Pediatric research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.
- A Systematic Literature Review of Factors Affecting the Timing of Menarche: The Potential for Climate Change to Impact Women's Health.International journal of environmental research and public health · 2020Pooled it
- Exploring the Health Effects of Phytoestrogens.Metabolites · 2026Review
- Association Between Selected Flavanols and Isoflavones and Precocious Puberty in Girls-A Scoping Review.Nutrients · 2026Article
- Development of the Chinese preschooler dietary index: a tool to assess overall diet quality.BMC public health · 2022Article
- Lignan exposure: a worldwide perspective.European journal of nutrition · 2022Review
- Article
- Pubertal Growth, IGF-1, and Windows of Susceptibility: Puberty and Future Breast Cancer Risk.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2021Article
- Modern dietary pattern is prospectively associated with earlier age at menarche: data from the CHNS 1997-2015.Nutrition journal · 2020Article
- Pubertal mammary development as a "susceptibility window" for breast cancer disparity.Advances in cancer research · 2020Review
- Communicating environmental exposure results and health information in a community-based participatory research study.BMC public health · 2018Article
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 1 country.
Funding
Abstract
BackgroundDietary phytoestrogens may alter hormonal activity in childhood. Flavonols and lignans are the most prevalent phytoestrogens in the Western diet. We examined whether higher intake of flavonols and lignans was associated with later age at menarche in a prospective study of young girls.MethodsIn all, 1,044 girls aged 6-8 years (mean 7.3 years) with two to four 24-h dietary recalls during their baseline year were followed up for 11 years until the attainment of menarche in the Breast Cancer and Environment Research Project (BCERP). Associations of age at menarche with quintiles of phytoestrogens were assessed using hazard ratios (HR) and 95% confidence intervals (CIs) from Cox proportional hazards models, controlling for body mass index and other covariates.ResultsThe highest quintile of flavonol intake was associated with a later age at menarche, compared with the lowest quintile (adjusted HR: 0.80, 95% CI: (0.66-1.00). For lignans, there was a later age in overweight girls (HR: 0.56, 95% CI=0.40-0.80).ConclusionThese dietary bioactives may reflect a healthy diet, and foods high in phytoestrogens may influence the timing of menarche.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.