Evidence map›Paper›PMID 28169418›Full record

Trial reportBritish journal of haematology2017

Allogeneic transplantation using CD34

Enkhtsetseg Purev, Xin Tian, Georg Aue, Jeremy Pantin, Phuong Vo, Reem Shalabi, Robert N Reger, Lisa Cook, Catalina Ramos, Elena Cho and 5 more

Open access · bronzeAbstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in British journal of haematology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Aplastic Anemia.The New England journal of medicine · 2018
    Review
  3. Diagnosis and Treatment of Aplastic Anemia.Current treatment options in oncology · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 1 country.

Enkhtsetseg PurevHematology Branch, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Xin TianOffice of Biostatistics Research, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Georg AueHematology Branch, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Jeremy PantinHematology and Oncology, Department of Medicine, Augusta University, Augusta, GA, USA.
Phuong VoHematology Branch, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Reem ShalabiClinical Center, Pharmacy Department, National Institutes of Health, Bethesda, MD, USA.
Robert N RegerHematology Branch, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Lisa CookHematology Branch, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Catalina RamosHematology Branch, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Elena ChoHematology Branch, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Tat'yana WorthyHematology Branch, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Hanh KhuuDepartment of Transfusion Medicine, National Institutes of Health, Bethesda, MD, USA.
David StroncekDepartment of Transfusion Medicine, National Institutes of Health, Bethesda, MD, USA.
Neal S YoungHematology Branch, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Richard W ChildsHematology Branch, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
National Institutes of Health · USNational Heart Lung and Blood Institute · USAugusta University Health · USNational Institutes of Health Clinical Center · US

Funding

Pathogenesis And Treatment Of Aplastic AnemiaZIAHL002315 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI YOUNG, NEAL S · 2009 to 2025
$60.1M
Allogeneic Immunotherapy for cancer and nonmalignant hematological disordersZIAHL002345 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI CHILDS, RICHARD · 2009 to 2025
$53.3M
Allogeneic Immunotherapy for cancer and nonmalignant hematological disordersZ01HL002345 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI CHILDS, RICHARD · 2000 to 2008
$6.5M
Cyclosporine Inhalation Solution (CIS) treatment of Bronchiolitis ObliteransZIAHL006090 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI CHILDS, RICHARD · 2010 to 2019
$3.9M
Intramural NIH HHS Z01 HL002345Intramural NIH HHS Z99 HL999999
6 · The paper itself

Abstract

Allogeneic haematopoietic stem cell transplantation is curative for severe aplastic anaemia (SAA) unresponsive to immunosuppressive therapy. To reduce chronic graft-versus-host disease (GVHD), which occurs more frequently after peripheral blood stem cell (PBSC) transplantation compared to bone-marrow transplantation (BMT), and to prevent graft rejection, we developed a novel partial T-cell depleted transplant that infuses high numbers of granulocyte colony-stimulating factor-mobilized CD34

Indexed as

Peripheral Blood Stem Cell TransplantationAdolescentAdultAgedAnemia, AplasticAntigens, CD34BiomarkersChildCohort StudiesCombined Modality TherapyFemaleGraft SurvivalGraft vs Host DiseaseHumansMaleMiddle AgedAntigens, CD34Biomarkersallogeneic stem cell transplantationbone marrow transplantationCD34+ selected PBSCpartial T-cell depleted transplantsevere aplastic anaemia

Identifiers

PMID28169418
PMCPMC7440634
OpenAlexW2587766008

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.