Evidence map›Paper›PMID 28169369›Full record

ArticleScientific reports2017

Fast and Quantitative T1ρ-weighted Dynamic Glucose Enhanced MRI.

Patrick Schuenke, Daniel Paech, Christina Koehler, Johannes Windschuh, Peter Bachert, Mark E Ladd, Heinz-Peter Schlemmer, Alexander Radbruch, Moritz Zaiss

Abstract readCase Reports
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Dynamic glucose-enhanced MRI in brain tumors.Magma (New York, N.Y.) · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Clinical MR Biomarkers.Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer · 2026
    Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. SPICY: a method for single scan rotating frame relaxometry.Physical chemistry chemical physics : PCCP · 2023
    Article
  19. Article
  20. Correction of errors in estimates of TNMR in biomedicine · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Patrick SchuenkeGerman Cancer Research Center (DKFZ), Division of Medical Physics in Radiology, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
Daniel PaechGerman Cancer Research Center (DKFZ), Division of Radiology, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
Christina KoehlerGerman Cancer Research Center (DKFZ), Division of Radiology, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
Johannes WindschuhGerman Cancer Research Center (DKFZ), Division of Medical Physics in Radiology, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
Peter BachertGerman Cancer Research Center (DKFZ), Division of Medical Physics in Radiology, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
Mark E LaddGerman Cancer Research Center (DKFZ), Division of Medical Physics in Radiology, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
Heinz-Peter SchlemmerGerman Cancer Research Center (DKFZ), Division of Radiology, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
Alexander RadbruchGerman Cancer Research Center (DKFZ), Division of Radiology, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
Moritz ZaissGerman Cancer Research Center (DKFZ), Division of Medical Physics in Radiology, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Common medical imaging techniques usually employ contrast agents that are chemically labeled, e.g. with radioisotopes in the case of PET, iodine in the case of CT or paramagnetic metals in the case of MRI to visualize the heterogeneity of the tumor microenvironment. Recently, it was shown that natural unlabeled D-glucose can be used as a nontoxic biodegradable contrast agent in Chemical Exchange sensitive Spin-Lock (CESL) magnetic resonance imaging (MRI) to detect the glucose uptake and potentially the metabolism of tumors. As an important step to fulfill the clinical needs for practicability, reproducibility and imaging speed we present here a robust and quantitative T

Indexed as

AgedBrainBrain NeoplasmsContrast MediaGlioblastomaGlucoseHumansImage EnhancementInjections, IntravenousMagnetic Resonance ImagingMalePhantoms, ImagingReproducibility of ResultsContrast MediaGlucose

Identifiers

PMID28169369
PMCPMC5294399

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.