ArticleScientific reports2017
Visualization of tumor-related blood vessels in human breast by photoacoustic imaging system with a hemispherical detector array.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 135 papers.
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Who cites it
135 citing papers in PubMed.
- Assessment of Breast Tumors Using Multispectral Optoacoustic Tomography in a Surgical Setting.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025Trial
- A virtual imaging framework for three-dimensional quantitative optoacoustic tomography using stochastic numerical breast phantoms.Photoacoustics · 2026Article
- Hybrid three-dimensional full-view multi-wavelength photoacoustic and ultrasound breast tomography.Photoacoustics · 2026Article
- Article
- Mapping the research landscape of photoacoustic imaging in breast cancer: a text-based bibliometric analysis.Gland surgery · 2026Article
- Optoacoustic muscle imaging.Journal of neuromuscular diseases · 2026Review
- Impact of skin pigmentation on photoacoustic tomography: a phantom study.Biophotonics discovery · 2026Article
- Photoacoustic Imaging of Vascular Structure After Breast Reconstruction with Autologous Fat Grafting: A Pilot Study.Journal of clinical medicine · 2026Article
- Photoacoustic imaging: An emerging tool for intraoperative margin assessment in breast-conserving surgery.Photoacoustics · 2026Review
- Motion score for spectral quality control of optoacoustic-ultrasound data.Scientific reports · 2026Article
- Learning a Filtered Backprojection Reconstruction Method for Photoacoustic Computed Tomography With Hemispherical Measurement Geometries.IEEE transactions on medical imaging · 2026Article
- A Hybrid Diffusion Model Enhances Multiparametric 3D Photoacoustic Computed Tomography.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- High-resolution three-dimensional quantitative photoacoustic and ultrasound imaging of subcutaneous microvasculature in extremities.Biomedical optics express · 2025Article
- Sinogram to image: direct reconstruction of photoacoustic tomography image using a hybrid deep learning approach.Biomedical optics express · 2025Article
- Advances in Photoacoustic Imaging of Breast Cancer.Sensors (Basel, Switzerland) · 2025Review
- Recent advancements in molecular photoacoustic tomography.JPhys photonics · 2025Review
- Ultrawideband high density polymer-based spherical array for real-time functional optoacoustic micro-angiography.Light, science & applications · 2025Article
- Utility of photoacoustic patterns in intra-operative margin assessment of breast cancer post neoadjuvant chemotherapy.Photoacoustics · 2025Article
- Is There a Role of Photoacoustic Imaging in Sports Medicine: Evidence Today.Orthopaedic surgery · 2025Review
- Wide-Field High-Speed Scanning Acoustic/Photoacoustic Microscopy for Whole-Body Imaging of Small Animals.Biosensors · 2025Article
75 more citing papers are in PubMed but not listed here.
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Authors and funding
20 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Noninvasive measurement of the distribution and oxygenation state of hemoglobin (Hb) inside the tissue is strongly required to analyze the tumor-associated vasculatures. We developed a photoacoustic imaging (PAI) system with a hemispherical-shaped detector array (HDA). Here, we show that PAI system with HDA revealed finer vasculature, more detailed blood-vessel branching structures, and more detailed morphological vessel characteristics compared with MRI by the use of breast shape deformation of MRI to PAI and their fused image. Morphologically abnormal peritumoral blood vessel features, including centripetal photoacoustic signals and disruption or narrowing of vessel signals, were observed and intratumoral signals were detected by PAI in breast cancer tissues as a result of the clinical study of 22 malignant cases. Interestingly, it was also possible to analyze anticancer treatment-driven changes in vascular morphological features and function, such as improvement of intratumoral blood perfusion and relevant changes in intravascular hemoglobin saturation of oxygen. This clinical study indicated that PAI appears to be a promising tool for noninvasive analysis of human blood vessels and may contribute to improve cancer diagnosis.
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