ArticleScientific reports2017
Ultra-high resolution profiles of macular intra-retinal layer thicknesses and associations with visual field defects in primary open angle glaucoma.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- The association between retina thinning and hippocampal atrophy in Alzheimer's disease and mild cognitive impairment: a meta-analysis and systematic review.Frontiers in aging neuroscience · 2023Pooled it
- Evaluation of the Diagnostic Capability of Spectralis SD-OCT 8 × 8 Posterior Pole Software with the Grid Tilted at 7 Degrees and Horizontalized in Glaucoma.Journal of clinical medicine · 2024Article
- The correlation of retinal neurodegeneration and brain degeneration in patients with Alzheimer's disease using optical coherence tomography angiography and MRI.Frontiers in aging neuroscience · 2023Article
- Article
- Glaucomatous Maculopathy: Thickness Differences on Inner and Outer Macular Layers between Ocular Hypertension and Early Primary Open-Angle Glaucoma Using 8 × 8 Posterior Pole Algorithm of SD-OCT.Journal of clinical medicine · 2020Article
- Correlation between brain volume and retinal photoreceptor outer segment volume in normal aging and neurodegenerative diseases.PloS one · 2020Article
- Reduced macular inner retinal thickness and microvascular density in the early stage of patients with dysthyroid optic neuropathy.Eye and vision (London, England) · 2020Article
- Early Macular Angiography among Patients with Glaucoma, Ocular Hypertension, and Normal Subjects.Journal of ophthalmology · 2019Article
- Optimizing a Portable ERG Device for Glaucoma Clinic: The Effect of Interstimulus Frequency on the Photopic Negative Response.Translational vision science & technology · 2018Article
- Analyzing the impact of glaucoma on the macular architecture using spectral-domain optical coherence tomography.PloS one · 2018Article
- Automated detection of photoreceptor disruption in mild diabetic retinopathy on volumetric optical coherence tomography.Biomedical optics express · 2017Article
- A new strategy to interpret OCT posterior pole asymmetry analysis for glaucoma diagnosis.International journal of ophthalmology · 2017Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The structural characteristics of the outer retinal layers in primary open angle glaucoma (POAG) are still controversial, and these changes, along with those in the inner retinal layers, could have clinical and/or pathophysiological significance. A custom-built ultra-high resolution optical coherence tomography (UHR-OCT) combined with an automated segmentation algorithm can image and measure the eight intra-retinal layers. The purpose of this study is to determine the thickness characteristics of the macular intra-retinal layers, especially the outer layers, in POAG patients. Thirty-four POAG patients (56 eyes) and 33 normal subjects (63 eyes) were enrolled. Thickness profiles of the eight intra-retinal layers along a 6-mm length centred on the fovea at the horizontal and vertical meridians were obtained and the regional thicknesses were compared between two groups. The associations between the thicknesses of each intra-retinal layer and the macular visual field (VF) sensitivity were then analysed. POAG affected not only the inner retinal layers but also the photoreceptor layers and retinal pigment epithelium of the outer retina. However, the VF loss was correlated mainly with the damage of the inner retinal layers. UHR-OCT with automated algorithm is a useful tool in detecting microstructural changes of macula with respect to the progression of glaucoma.
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