Evidence map›Paper›PMID 28168652›Full record

ArticleJournal of cardiovascular translational research2017

Impaired Tissue Oxygenation in Metabolic Syndrome Requires Increased Microvascular Perfusion Heterogeneity.

P Mason McClatchey, Fan Wu, I Mark Olfert, Christopher G Ellis, Daniel Goldman, Jane E B Reusch, Jefferson C Frisbee

Open access · greenAbstract read
In one paragraph

Article in Journal of cardiovascular translational research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 23 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Automated quantification of microvascular perfusion.Microcirculation (New York, N.Y. : 1994) · 2018
    Article
  10. Exercise intolerance in Type 2 diabetes: is there a cardiovascular contribution?Journal of applied physiology (Bethesda, Md. : 1985) · 2018
    Review
  11. Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

P Mason McClatcheyDivision of Endocrinology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Fan WuDrug Metabolism and Pharmacokinetics, Novartis Institutes for BioMedical Research, East Hanover, NJ, USA.
I Mark OlfertDivision of Exercise Physiology, West Virginia University Health Sciences Center, Morgantown, WV, USA.
Christopher G EllisDepartment of Medical Biophysics, Schulich School of Medicine and Dentistry, University of Western Ontario, Medical Sciences Building, M407, 1151 Richmond Street North, London, ON, N6A 5C1, Canada.
Daniel GoldmanDepartment of Medical Biophysics, Schulich School of Medicine and Dentistry, University of Western Ontario, Medical Sciences Building, M407, 1151 Richmond Street North, London, ON, N6A 5C1, Canada.
Jane E B ReuschDepartment of Bioengineering, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Jefferson C FrisbeeDepartment of Medical Biophysics, Schulich School of Medicine and Dentistry, University of Western Ontario, Medical Sciences Building, M407, 1151 Richmond Street North, London, ON, N6A 5C1, Canada. jfrisbee@uwo.ca.
Western University · CAUniversity of Colorado Anschutz Medical Campus · USWest Virginia University · US

Funding

Cardiovascular Biomechanics and Imaging in Down SyndromeT32HL072738 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI SHANDAS, ROBIN · 2003 to 2025
$4.9M
Skeletal Muscle Microcirculation in Obese Zucker RatsR01DK064668 · NIDDK · WEST VIRGINIA UNIVERSITY · PI FRISBEE, JEFFERSON C · 2004 to 2009
$1.1M
Targeting Microvascular Contributors to Impaired Functional Exercise Capacity in DiabetesI01BX002046 · VA · VA EASTERN COLORADO HEALTH CARE SYSTEM · PI REUSCH, JANE E · 2014 to 2024
–
Cardiovascular Mechanisms of Exercise Intolerance in Diabetes and the Role of SexI01CX001532 · VA · VA EASTERN COLORADO HEALTH CARE SYSTEM · PI REUSCH, JANE E · 2017 to 2022
–
BLRD VA I01 BX002046CSRD VA I01 CX001532NHLBI NIH HHS T32 HL072738NIDDK NIH HHS R01 DK064668
6 · The paper itself

Abstract

Metabolic syndrome (MS) in obese Zucker rats (OZR) is associated with impaired skeletal muscle performance and blunted hyperemia. Studies suggest that reduced O

Indexed as

MicrocirculationModels, CardiovascularMuscle ContractionAnimalsBlood Flow VelocityCell HypoxiaComputer SimulationDisease Models, AnimalKineticsMetabolic SyndromeMicrovesselsMuscle, SkeletalObesityOxygenOxygen ConsumptionRats, ZuckerOxygenBlood flow controlMicrocirculationOxygenationRodent models of obesitySimulation

Identifiers

PMID28168652
PMCPMC5893163
OpenAlexW2586434058

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.