Evidence map›Paper›PMID 28168572›Full record

ArticleAMB Express2017

Expression, purification and functionality of bioactive recombinant human vascular endothelial growth factor VEGF

Awatef Taktak-BenAmar, Maram Morjen, Hazem Ben Mabrouk, Rania Abdelmaksoud-Dammak, Mohamed Guerfali, Najla Fourati-Masmoudi, Naziha Marrakchi, Ali Gargouri

Abstract read
In one paragraph

Article in AMB Express, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Growth Factors VEGF-AInternational journal of molecular sciences · 2021
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Awatef Taktak-BenAmarLaboratoire de Biotechnologie Moléculaire des Eucaryotes, Centre de Biotechnologie de Sfax, University of Sfax, BP1177, 3018, Sfax, Tunisia.
Maram MorjenLaboratoire des Venins et Biomolécules Thérapeutiques, LR11IPT08, Institut Pasteur de Tunis, Université de Tunis el Manar, 13, Place Pasteur, 1002, Tunis, Tunisia.
Hazem Ben MabroukLaboratoire des Venins et Biomolécules Thérapeutiques, LR11IPT08, Institut Pasteur de Tunis, Université de Tunis el Manar, 13, Place Pasteur, 1002, Tunis, Tunisia.
Rania Abdelmaksoud-DammakLaboratoire de Biotechnologie Moléculaire des Eucaryotes, Centre de Biotechnologie de Sfax, University of Sfax, BP1177, 3018, Sfax, Tunisia.
Mohamed GuerfaliLaboratoire de Biotechnologie Moléculaire des Eucaryotes, Centre de Biotechnologie de Sfax, University of Sfax, BP1177, 3018, Sfax, Tunisia.
Najla Fourati-MasmoudiService Analyse, Centre de Biotechnologie de Sfax, University of Sfax, BP1177, 3018, Sfax, Tunisia.
Naziha MarrakchiLaboratoire des Venins et Biomolécules Thérapeutiques, LR11IPT08, Institut Pasteur de Tunis, Université de Tunis el Manar, 13, Place Pasteur, 1002, Tunis, Tunisia.
Ali GargouriLaboratoire de Biotechnologie Moléculaire des Eucaryotes, Centre de Biotechnologie de Sfax, University of Sfax, BP1177, 3018, Sfax, Tunisia. faouzi.gargouri@cbs.rnrt.tn.ORCID http://orcid.org/0000-0001-5009-9000

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vascular endothelial growth factor (VEGF) is associated with tumour growth and metastasis. Because VEGF is the major player in both angiogenesis and vascular permeability and the most explored factor in angio-inhibitory therapies, many expression procedures have been developed to produce functional VEGF

Indexed as

CAM assayCell migration and proliferationInclusion bodiesPurificationRefoldingRT-PCRSoluble VEGF165 expression

Identifiers

PMID28168572
PMCPMC5293700

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.