ArticleClinical autonomic research : official journal of the Clinical Autonomic Research Society2017
Health-related quality of life and suicide risk in postural tachycardia syndrome.
Article in Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03974737 (Evaluation of the Compensatory Reserve Index and Psychosocial Factors in Pediatric Autonomic Dysfunction), which is not on this map. Cited by 24 papers, 3 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Evaluation of the Compensatory Reserve Index and Psychosocial Factors in Pediatric Autonomic Dysfunction
Who cites it
24 citing papers in PubMed, 3 syntheses or guidelines pooled it, 53 citations in OpenAlex.
- Faintly tired: a systematic review of fatigue in patients with orthostatic syncope.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2022Pooled it
- Evaluating the Impact of Orthostatic Syncope and Presyncope on Quality of Life: A Systematic Review and Meta-Analysis.Frontiers in cardiovascular medicine · 2022Pooled it
- Gastrointestinal symptoms in postural tachycardia syndrome: a systematic review.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2018Pooled it
- Midodrine exposure trends and outcomes reported to United States poison centers: 2000-2023.Clinical toxicology (Philadelphia, Pa.) · 2025Article
- Long-COVID and postural orthostatic tachycardia syndrome: a preliminary comparison of neuropsychological performance.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2025Article
- Nomogram and scoring models based on BMI z-score, serum chlorine and urine specific gravity levels for predicting oral rehydration solution efficacy in pediatric postural orthostatic tachycardia syndrome.World journal of pediatrics : WJP · 2025Article
- Quality of life and physical/psychosocial factors in children and adolescents with orthostatic intolerance.BioPsychoSocial medicine · 2023Article
- Experiences of living with postural tachycardia syndrome.Chronic illness · 2023Article
- Comparisons of heart rate variability responses to head-up tilt with and without abdominal and lower-extremity compression in healthy young individuals: a randomized crossover study.Frontiers in physiology · 2023Article
- Children With PANS May Manifest POTS.Frontiers in neurology · 2022Article
- Orthostatic intolerance syndromes after hematopoietic cell transplantation: clinical characteristics and therapeutic interventions in a single-center experience.Cardio-oncology (London, England) · 2021Article
- Postural orthostatic tachycardia syndrome is associated with significant employment and economic loss.Journal of internal medicine · 2021Article
- Management of orthostatic intolerance in children: the state of the art.World journal of pediatrics : WJP · 2020Article
- Work Ability Assessment and Its Relationship with Cardiovascular Autonomic Profile in Postural Orthostatic Tachycardia Syndrome.International journal of environmental research and public health · 2020Article
- ST-segment changes during tilt-table testing in postural tachycardia syndrome: are they relevant?Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2020Article
- Postural Orthostatic Tachycardia Syndrome.Texas Heart Institute journal · 2020Review
- The face of postural tachycardia syndrome - insights from a large cross-sectional online community-based survey.Journal of internal medicine · 2019Article
- Long-Term Outcomes of Children and Adolescents With Postural Tachycardia Syndrome After Conventional Treatment.Frontiers in pediatrics · 2019Article
- Autonomic dysfunction in sleep disorders: introduction to the series.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2018Article
- Cognitive and psychological issues in postural tachycardia syndrome.Autonomic neuroscience : basic & clinical · 2018Review
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposePostural tachycardia syndrome (POTS) is a disorder featured by orthostatic intolerance. The purpose of this study was to investigate the severity of quality of life issues in POTS patients.
methodsOnline surveys for health related quality of life, sleep quality, fatigue, pain, and suicidal ideation were completed by 624 POTS patients and 139 controls.
resultsPeople with POTS have significantly more days of poor physical health (p < 0.001), fewer days with good energy (p < 0.001), and significantly more days with activity limitations (p < 0.001) than controls. Pain severity was significantly higher for those with POTS (p < 0.001) while feelings of control over life was lower than controls (p < 0.001). Sleep quality and daytime fatigue were also significantly worse for those with POTS than controls (p < 0.001). Finally, those with POTS have a significantly higher risk of suicide compared with controls (p < 0.001).
interpretationThe myriad of symptoms from which many POTS patients suffer is associated with a decreased quality of life. Nearly half of our sample with POTS was at high risk for suicide. More work needs to be done to determine the underlying issues surrounding suicide in POTS so that an appropriate treatment regimen can be developed.
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