Evidence map›Paper›PMID 28168443›Full record

ArticleCellular and molecular life sciences : CMLS2017

Crystal structure and biochemical characterization of the transmembrane PAP2 type phosphatidylglycerol phosphate phosphatase from Bacillus subtilis.

Meriem El Ghachi, Nicole Howe, Rodolphe Auger, Alexandre Lambion, Annick Guiseppi, François Delbrassine, Guillaume Manat, Sophie Roure, Sabine Peslier, Eric Sauvage and 8 more

Open access · greenAbstract read
In one paragraph

Article in Cellular and molecular life sciences : CMLS, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
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  3. ThemBio · 2026
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  6. PgpP is a broadly conserved phosphatase required for phosphatidylglycerol lipid synthesis.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  7. Article
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  10. Characterization of the Streptococcus mutansJournal of bacteriology · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 8 institutions in 3 countries.

Meriem El GhachiCentre d'Ingénierie des Protéines, InBioS, Université de Liège, allée du 6 Août 19, Bât B5a, 4000, Liège, Belgium.
Nicole HoweMembrane Structural and Functional Biology Group, Schools of Medicine and Biochemistry and Immunology, Trinity College Dublin, Dublin 2, Ireland.
Rodolphe AugerInstitute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Univ Paris-Sud, Université Paris-Saclay, 91198, Gif-sur-Yvette cedex, France.
Alexandre LambionCentre d'Ingénierie des Protéines, InBioS, Université de Liège, allée du 6 Août 19, Bât B5a, 4000, Liège, Belgium.
Annick GuiseppiLaboratoire de Chimie Bactérienne UMR 7283, Aix-Marseille Université, Marseille, France.
François DelbrassineCentre d'Ingénierie des Protéines, InBioS, Université de Liège, allée du 6 Août 19, Bât B5a, 4000, Liège, Belgium.
Guillaume ManatInstitute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Univ Paris-Sud, Université Paris-Saclay, 91198, Gif-sur-Yvette cedex, France.
Sophie RoureInstitute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Univ Paris-Sud, Université Paris-Saclay, 91198, Gif-sur-Yvette cedex, France.
Sabine PeslierLaboratoire de Chimie Bactérienne UMR 7283, Aix-Marseille Université, Marseille, France.
Eric SauvageCentre d'Ingénierie des Protéines, InBioS, Université de Liège, allée du 6 Août 19, Bât B5a, 4000, Liège, Belgium.
Lutz VogeleyMembrane Structural and Functional Biology Group, Schools of Medicine and Biochemistry and Immunology, Trinity College Dublin, Dublin 2, Ireland.
Juan-Carlos Rengifo-GonzalezCentre d'Ingénierie des Protéines, InBioS, Université de Liège, allée du 6 Août 19, Bât B5a, 4000, Liège, Belgium.
Paulette CharlierCentre d'Ingénierie des Protéines, InBioS, Université de Liège, allée du 6 Août 19, Bât B5a, 4000, Liège, Belgium.
Dominique Mengin-LecreulxInstitute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Univ Paris-Sud, Université Paris-Saclay, 91198, Gif-sur-Yvette cedex, France.
Maryline FoglinoLaboratoire de Chimie Bactérienne UMR 7283, Aix-Marseille Université, Marseille, France.
Thierry TouzéInstitute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Univ Paris-Sud, Université Paris-Saclay, 91198, Gif-sur-Yvette cedex, France. thierry.touze@i2bc.paris-saclay.fr.
Martin CaffreyMembrane Structural and Functional Biology Group, Schools of Medicine and Biochemistry and Immunology, Trinity College Dublin, Dublin 2, Ireland. martin.caffrey@tcd.ie.
Frédéric KerffCentre d'Ingénierie des Protéines, InBioS, Université de Liège, allée du 6 Août 19, Bât B5a, 4000, Liège, Belgium. fkerff@ulg.ac.be.
University of Liège · BETrinity College Dublin · IEAix-Marseille Université · FRCEA Paris-Saclay · FRCentre National de la Recherche Scientifique · FRCommissariat à l'Énergie Atomique et aux Énergies Alternatives · FRLaboratoire de Chimie Bactérienne · FRUniversité Paris-Saclay · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Type 2 phosphatidic acid phosphatases (PAP2s) can be either soluble or integral membrane enzymes. In bacteria, integral membrane PAP2s play major roles in the metabolisms of glycerophospholipids, undecaprenyl-phosphate (C

Indexed as

Bacillus subtilisCatalytic DomainCell MembraneCrystallography, X-RayEscherichia coliGenes, BacterialGenetic Complementation TestModels, MolecularMutagenesis, Site-DirectedPhosphatidate PhosphatasePhosphatidylglycerolsSolubilitySubstrate SpecificityPhosphatidate Phosphatasephosphatidic acid phosphatase type 2PhosphatidylglycerolsphosphatidylglycerophosphateBacterial lipids metabolismMembrane protein structurePeptidoglycan-related lipidUndecaprenyl phosphate

Identifiers

PMID28168443
PMCPMC11107685
OpenAlexW2587614499

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.