ArticleCerebral cortex (New York, N.Y. : 1991)2017
Positive and Negative Somatotopic BOLD Responses in Contralateral Versus Ipsilateral Penfield Homunculus.
Article in Cerebral cortex (New York, N.Y. : 1991), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
21 citing papers in PubMed.
- Sensory-Discriminative Three-Dimensional Body Pain Mobile App Measures Versus Traditional Pain Measurement With a Visual Analog Scale: Validation Study.JMIR mHealth and uHealth · 2020Trial
- The Neural Organization of Visual Information in the Auditory Cortex of the Congenitally Deaf.Human brain mapping · 2026Article
- Cerebro-spinal somatotopic organization uncovered through functional connectivity mapping.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Loss of action-related function and connectivity in the blind extrastriate body area.Frontiers in neuroscience · 2023Article
- Pain-related reorganization in the primary somatosensory cortex of patients with postherpetic neuralgia.Human brain mapping · 2022Article
- Spatial probability maps of the segments of the postcentral sulcus in the human brain.Cerebral cortex (New York, N.Y. : 1991) · 2022Article
- Altruistic acting caused by a touching hand: neural underpinnings of the Midas touch effect.Social cognitive and affective neuroscience · 2022Article
- Moving in on human motor cortex. Characterizing the relationship between body parts with non-rigid population response fields.PLoS computational biology · 2022Article
- Beyond body maps: Information content of specific body parts is distributed across the somatosensory homunculus.Cell reports · 2022Article
- Characterization of cortical hemodynamic changes following sensory, visual, and speech activation by intraoperative optical imaging utilizing phase-based evaluation methods.Human brain mapping · 2022Article
- Aura Mapping: Where Vision and Somatosensation Meet.Vision (Basel, Switzerland) · 2021Article
- Aberrant somatosensory phase synchronization in children with hemiplegic cerebral palsy.Neuroscience letters · 2021Article
- A touch of hierarchy: population receptive fields reveal fingertip integration in Brodmann areas in human primary somatosensory cortex.Brain structure & function · 2021Article
- Review
- Tight Coupling between Morphological Features of the Central Sulcus and Somatomotor Body Representations: A Combined Anatomical and Functional MRI Study.Cerebral cortex (New York, N.Y. : 1991) · 2020Article
- Disinhibition of Human Primary Somatosensory Cortex After Median Nerve Transection and Reinnervation.Frontiers in human neuroscience · 2020Article
- Fine-Grained Mapping of Cortical Somatotopies in Chronic Complex Regional Pain Syndrome.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Article
- Egomotion-related visual areas respond to active leg movements.Human brain mapping · 2019Article
- Differential Effects of Sustained Manual Pressure Stimulation According to Site of Action.Frontiers in neuroscience · 2019Article
- Preferential encoding of movement amplitude and speed in the primary motor cortex and cerebellum.Human brain mapping · 2017Article
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3 authors.
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Abstract
One of the basic properties of sensory cortices is their topographical organization. Most imaging studies explored this organization using the positive blood oxygenation level-dependent (BOLD) signal. Here, we studied the topographical organization of both positive and negative BOLD in contralateral and ipsilateral primary somatosensory cortex (S1). Using phase-locking mapping methods, we verified the topographical organization of contralateral S1, and further showed that different body segments elicit pronounced negative BOLD responses in both hemispheres. In the contralateral hemisphere, we found a sharpening mechanism in which stimulation of a given body segment triggered a gradient of activation with a significant deactivation in more remote areas. In the ipsilateral cortex, deactivation was not only located in the homolog area of the stimulated parts but rather was widespread across many parts of S1. Additionally, analysis of resting-state functional magnetic resonance imaging signal showed a gradient of connectivity to the neighboring contralateral body parts as well as to the ipsilateral homologous area for each body part. Taken together, our results indicate a complex pattern of baseline and activity-dependent responses in the contralateral and ipsilateral sides. Both primary sensory areas were characterized by unique negative BOLD responses, suggesting that they are an important component in topographic organization of sensory cortices.
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