Evidence map›Paper›PMID 28168174›Full record

ArticleClinical and experimental vaccine research2017

SH2 domain-containing adaptor protein B expressed in dendritic cells is involved in T-cell homeostasis by regulating dendritic cell-mediated Th2 immunity.

Md Selim Ahmed, Myeong-Ho Kang, Ezra Lee, Yujin Park, Yideul Jeong, Yong-Soo Bae

Open access · diamondAbstract read
In one paragraph

Article in Clinical and experimental vaccine research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Dendritic Cell-Mediated Th2 Immunity and Immune Disorders.International journal of molecular sciences · 2019
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Md Selim AhmedDepartment of Biological Science, Sungkyunkwan University, Suwon, Korea.ORCID 0000-0002-9601-8031
Myeong-Ho KangDepartment of Biological Science, Sungkyunkwan University, Suwon, Korea.ORCID 0000-0001-5877-9916
Ezra LeeDepartment of Biological Science, Sungkyunkwan University, Suwon, Korea.ORCID 0000-0003-4508-9371
Yujin ParkDepartment of Biological Science, Sungkyunkwan University, Suwon, Korea.ORCID 0000-0002-7696-4194
Yideul JeongDepartment of Biological Science, Sungkyunkwan University, Suwon, Korea.ORCID 0000-0002-2667-9256
Yong-Soo BaeDepartment of Biological Science, Sungkyunkwan University, Suwon, Korea.ORCID 0000-0002-2233-9449
Sungkyunkwan University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe Src homology 2 domain-containing adaptor protein B (SHB) is widely expressed in immune cells and acts as an important regulator for hematopoietic cell function. SHB silencing induces Th2 immunity in mice. SHB is also involved in T-cell homeostasis MATERIALS AND

methodsThe effects of SHB expression on the immunogenicity of DCs were assessed by

resultsSHB was steadily expressed in mouse splenic DCs and in

conclusionSHB expression in DCs plays an important role in T-cell homeostasis

Indexed as

Atopic dermatitisDendritic cellsSHBTh2 immunity

Identifiers

PMID28168174
PMCPMC5292358
OpenAlexW2584857544

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.