ArticlePeerJ2017
Comparison of admission random glucose, fasting glucose, and glycated hemoglobin in predicting the neurological outcome of acute ischemic stroke: a retrospective study.
Article in PeerJ, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
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Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 39 citations in OpenAlex.
- Association of the Stress Hyperglycemia Ratio and Prognosis After Endovascular Treatment: A Systematic Review and Meta-Analysis.Brain and behavior · 2026Pooled it
- Prevalence of diabetes and its effects on stroke outcomes: A meta-analysis and literature review.Journal of diabetes investigation · 2019Pooled it
- Integrating GLP-1 Receptor Agonists into Modern Stroke Prevention: Evidence, Mechanisms, and Clinical Consideration-A Narrative Review.Biomedicines · 2026Review
- The relationship between HbA1c and the functional outcome of acute ischemic stroke: A prospective cohort study.Current journal of neurology · 2025Article
- Acute-to-chronic glycemic ratio as an outcome predictor in ischemic stroke in patients with and without diabetes mellitus.Cardiovascular diabetology · 2024Article
- Relationship between glycated hemoglobin levels and three-month outcomes in acute ischemic stroke patients with or without diabetes: a prospective Korean cohort study.BMC neurology · 2024Article
- Performance comparison of stress hyperglycemia ratio for predicting fatal outcomes in patients with thrombolyzed acute ischemic stroke.PloS one · 2024Article
- XGBoost-Based Simple Three-Item Model Accurately Predicts Outcomes of Acute Ischemic Stroke.Diagnostics (Basel, Switzerland) · 2023Article
- The association between stress hyperglycemia and unfavorable outcomes in patients with anterior circulation stroke after mechanical thrombectomy.Frontiers in aging neuroscience · 2022Article
- The acute-to-chronic glycemic ratio correlates with the severity of illness at admission in patients with diabetes experiencing acute ischemic stroke.Frontiers in neurology · 2022Article
- Association Between Raised HbA1c Levels and Hemorrhagic Transformation in Patients With Ischemic Stroke.Cureus · 2021Article
- Carotid intima media thickness measurements coupled with stroke severity strongly predict short-term outcome in patients with acute ischemic stroke: a machine learning study.Metabolic brain disease · 2021Article
- Elevated Glycated Hemoglobin Levels Are Associated With Poor Outcome in Acute Ischemic Stroke.Frontiers in aging neuroscience · 2021Article
- Recurrent Ischemic and Hemorrhagic Stroke in Cameroon: A Case-Control Study.Neurology research international · 2021Article
- Observational
- Development and validation of a new score for predicting functional outcome of neurocritically ill patients: The INCNS score.CNS neuroscience & therapeutics · 2020Article
- A Novel INCNS Score for Prediction of Mortality and Functional Outcome of Comatose Patients.Frontiers in neurology · 2020Article
- Elevated plasma D-dimer levels are associated with short-term poor outcome in patients with acute ischemic stroke: a prospective, observational study.BMC neurology · 2019Observational
- Prediction of the Lethal Outcome of Acute Recurrent Cerebral Ischemic Hemispheric Stroke.Medicina (Kaunas, Lithuania) · 2019Article
- Observation of elevated fasting blood glucose and functional outcome after ischemic stroke in patients with and without diabetes.Oncotarget · 2017Article
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHyperglycemia is a known predictor of negative outcomes in stroke. Several glycemic measures, including admission random glucose, fasting glucose, and glycated hemoglobin (HbA1c), have been associated with bad neurological outcomes in acute ischemic stroke, particularly in nondiabetic patients. However, the predictive power of these glycemic measures is yet to be investigated.
methodsThis retrospective study enrolled 484 patients with acute ischemic stroke from January 2009 to March 2013, and complete records of initial stroke severity, neurological outcomes at three months, and glycemic measures were evaluated. We examined the predictive power of admission random glucose, fasting glucose, and HbA1c for neurological outcomes in acute ischemic stroke. Furthermore, subgroup analyses of nondiabetic patients and patients with diabetes were performed separately.
resultsReceiver operating characteristic (ROC) analysis revealed that admission random glucose and fasting glucose were significant predictors of poor neurological outcomes, whereas HbA1c was not (areas under the ROC curve (AUCs): admission random glucose = 0.564, DISCUSSION: Fasting glucose is an independent predictor of poor neurological outcomes in patients with acute ischemic stroke and had greater predictive power than that of admission random glucose and HbA1c. The predictive power of glycemic measures for poor neurological outcomes did not differ significantly between the nondiabetic patients and those with diabetes.
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