Evidence map›Paper›PMID 28168080›Full record

ArticleJournal of osteoporosis2017

The Femoral Neck Mechanoresponse to Hip Extensors Exercise: A Case Study.

Saulo Martelli, Hossein Mokhtarzadeh, Peter Pivonka, Peter R Ebeling

Open access · goldAbstract read
In one paragraph

Article in Journal of osteoporosis, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Femoral Neck Strain during Maximal Contraction of Isolated Hip-Spanning Muscle Groups.Computational and mathematical methods in medicine · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Saulo MartelliSchool of Computer Science, Engineering and Mathematics, Flinders University, Adelaide, SA, Australia; North West Academic Centre, The University of Melbourne, St Albans, VIC, Australia.ORCID 0000-0002-0012-8122
Hossein MokhtarzadehDepartment of Orthopedic Surgery, Harvard Medical School and Center for Advanced Orthopaedic Studies, Beth Israel Deaconess Medical Center, Boston, MA, USA; Department of Mechanical Engineering, Melbourne School of Engineering, University of Melbourne, Parkville, VIC, Australia.
Peter PivonkaNorth West Academic Centre, The University of Melbourne, St Albans, VIC, Australia; Australian Institute for Musculoskeletal Science, St Albans, VIC, Australia; St Vincent's Department of Surgery, The University of Melbourne, Fitzroy, VIC, Australia.
Peter R EbelingAustralian Institute for Musculoskeletal Science, St Albans, VIC, Australia; Department of Medicine, School of Clinical Sciences, Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton, VIC, Australia.
The University of Melbourne · AUAustralian Institute for Musculoskeletal Science · AUBeth Israel Deaconess Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Physical activity is recommended to prevent age-related bone loss. However, the proximal femur mechanoresponse is variable, possibly because of a muscle-dependant mechanoresponse. We compared the proximal femur response with the femoral strain pattern generated by the hip extensor muscles. A healthy participant underwent a six-month unilateral training of the hip extensor muscles using a resistance weight regularly adjusted to the 80% of the one-repetition maximum weight. DXA-based measurements of the areal Bone Mineral Density (aBMD) in the exercise leg were adjusted for changes in the control leg. The biomechanical stimulus for bone adaptation (BS) was calculated using published models of the musculoskeletal system and the average hip extension moment in elderly participants. Volumetric (ΔvBMD) and areal (ΔaBMD) BMD changes were calculated. The measured and calculated BMD changes consistently showed a positive and negative effect of exercise in the femoral neck (ΔaBMD = +0.7%; ΔvBMD = +0.8%) and the trochanter region (ΔaBMD = -4.1%; ΔvBMD = -0.5%), respectively. The 17% of the femoral neck exceeded the 75th percentile of the spatially heterogeneous BS distribution. Hip extensor exercises may be beneficial in the proximal femoral neck but not in the trochanteric region. DXA-based measurements may not capture significant aBMD local changes.

Identifiers

PMID28168080
PMCPMC5267078
OpenAlexW2573341496

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.