Evidence map›Paper›PMID 28168012›Full record

ReviewOxidative medicine and cellular longevity2017

Nutrition and AGE-ing: Focusing on Alzheimer's Disease.

Giulia Abate, Mariagrazia Marziano, Wiramon Rungratanawanich, Maurizio Memo, Daniela Uberti

Registry-linked trialOpen access · hybridAbstract readReview
In one paragraph

Review in Oxidative medicine and cellular longevity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04908163 (Feasibility Study for the Development of a Nutritional-culinary Programme to Tackle Overweight or Obesity as a Strategy to Promote Adherence to a Healthy Dietary Pattern.), which is not on this map. Cited by 29 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 2 pooled it
8.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04908163 nacompletednot on this mapstarted 2021, after this paper: background citation

Feasibility Study for the Development of a Nutritional-culinary Programme to Tackle Overweight or Obesity as a Strategy to Promote Adherence to a Healthy Dietary Pattern.

TypeinterventionalSponsorBasque Culinary Center FundazioaRan2021 to 2022Enrolled56ConditionsObesity, Healthy Aging, Cognitive ImpairmentArmsMediterranean diet-based nutritional education intervention, Mediterranean diet-based culinary intervention
3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 101 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Glycative stress as a cause of macular degeneration.Progress in retinal and eye research · 2024
    Review
  5. Article
  6. Review
  7. The Effects ofInternational journal of molecular sciences · 2023
    Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. In Pursuit of Healthy Aging: Effects of Nutrition on Brain Function.International journal of molecular sciences · 2021
    Review
  13. Review
  14. Review
  15. Article
  16. Review
  17. Review
  18. Observational
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 2 countries.

Giulia AbateDepartment of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.ORCID 0000-0001-9161-3475
Mariagrazia MarzianoDepartment of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.
Wiramon RungratanawanichDepartment of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.
Maurizio MemoDepartment of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.
Daniela UbertiDepartment of Molecular and Translational Medicine, University of Brescia, Brescia, Italy; Diadem Ltd., Spin Off of Brescia University, Viale Europa 11, 25123 Brescia, Italy.ORCID 0000-0002-5926-9122
Brescia University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recently, the role of food and nutrition in preventing or delaying chronic disability in the elderly population has received great attention. Thanks to their ability to influence biochemical and biological processes, bioactive nutrients are considered modifiable factors capable of preserving a healthy brain status. A diet rich in vitamins and polyphenols and poor in saturated fatty acids has been recommended. In the prospective of a healthy diet, cooking methods should be also considered. In fact, cooking procedures can modify the original dietary content, contributing not only to the loss of healthy nutrients, but also to the formation of toxins, including advanced glycation end products (AGEs). These harmful compounds are adsorbed at intestinal levels and can contribute to the ageing process. The accumulation of AGEs in ageing ("AGE-ing") is further involved in the exacerbation of neurodegenerative and many other chronic diseases. In this review, we discuss food's dual role as both source of bioactive nutrients and reservoir for potential toxic compounds-paying particular attention to the importance of proper nutrition in preventing/delaying Alzheimer's disease. In addition, we focus on the importance of a good education in processing food in order to benefit from the nutritional properties of an optimal diet.

Indexed as

AgedAlzheimer DiseaseDietDisease ProgressionGlycation End Products, AdvancedHumansNutritional StatusGlycation End Products, Advanced

Identifiers

PMID28168012
PMCPMC5266861
OpenAlexW2576784305

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.