Evidence map›Paper›PMID 28168008›Full record

ReviewOxidative medicine and cellular longevity2017

Protective Effect of Antioxidants on Neuronal Dysfunction and Plasticity in Huntington's Disease.

Thirunavukkarasu Velusamy, Archana S Panneerselvam, Meera Purushottam, Muthuswamy Anusuyadevi, Pramod Kumar Pal, Sanjeev Jain, Musthafa Mohamed Essa, Gilles J Guillemin, Mahesh Kandasamy

Open access · hybridAbstract readReview
In one paragraph

Review in Oxidative medicine and cellular longevity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 51 citations in OpenAlex.

  1. Review
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  10. Antioxidant and Anti-Inflammatory Effects ofAntioxidants (Basel, Switzerland) · 2020
    Review
  11. Review
  12. PPARγ and Cognitive Performance.International journal of molecular sciences · 2019
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 3 countries.

Thirunavukkarasu VelusamyDepartment of Biotechnology, Bharathiar University, Coimbatore, Tamil Nadu, India; DBT Ramalingaswami Re-Entry Fellowship Programme, Department of Biotechnology (DBT), New Delhi, India.
Archana S PanneerselvamLaboratory of Stem Cells and Neuroregeneration, Department of Animal Science, School of Life Sciences, Bharathidasan University, Tiruchirappalli, Tamil Nadu, India.
Meera PurushottamDepartment of Psychiatry, National Institute of Mental Health and Neurosciences (NIMHANS), Bangalore, Karnataka, India.
Muthuswamy AnusuyadeviMolecular Gerontology Laboratory, Department of Biochemistry, School of Life Sciences, Bharathidasan University, Tiruchirappalli, Tamil Nadu, India.
Pramod Kumar PalDepartment of Neurology, National Institute of Mental Health and Neurosciences (NIMHANS), Bangalore, Karnataka, India.
Sanjeev JainDepartment of Psychiatry, National Institute of Mental Health and Neurosciences (NIMHANS), Bangalore, Karnataka, India.
Musthafa Mohamed EssaDepartment of Food Science and Nutrition, CAMS, Sultan Qaboos University, Muscat, Oman.
Gilles J GuilleminNeuroinflammation Group, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, NSW, Australia.ORCID 0000-0001-8105-4470
Mahesh KandasamyLaboratory of Stem Cells and Neuroregeneration, Department of Animal Science, School of Life Sciences, Bharathidasan University, Tiruchirappalli, Tamil Nadu, India; UGC-Faculty Recharge Program (UGC-FRP), University Grant Commission, New Delhi, India.ORCID 0000-0002-6720-9082
National Institute of Mental Health and Neurosciences · INBharathidasan University · INBharathiar University · INMacquarie University · AUSultan Qaboos University · OMUniversity Grants Commission · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Huntington's disease (HD) is characterised by movement disorders, cognitive impairments, and psychiatric problems. The abnormal generation of reactive oxygen species and the resulting oxidative stress-induced mitochondrial damage in neurons upon CAG mutations in the

Indexed as

AnimalsAntioxidantsHumansHuntington DiseaseMiceNeurodegenerative DiseasesOxidative StressRatsReactive Oxygen SpeciesAntioxidantsReactive Oxygen Species

Identifiers

PMID28168008
PMCPMC5266860
OpenAlexW2573769761

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.