Evidence map›Paper›PMID 28167895›Full record

ArticleTobacco induced diseases2017

A comparison of the efficacy of varenicline and bupropion and an evaluation of the effect of the medications in the context of the smoking cessation programme.

Ali Ramazan Benli, Selman Erturhan, Muhammet Ali Oruc, Pinar Kalpakci, Didem Sunay, Yeltekin Demirel

Open access · goldAbstract read
In one paragraph

Article in Tobacco induced diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 3 pooled it
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 3 syntheses or guidelines pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Nicotine receptor partial agonists for smoking cessation.The Cochrane database of systematic reviews · 2023
    Pooled it
  3. Antidepressants for smoking cessation.The Cochrane database of systematic reviews · 2020
    Pooled it
  4. Article
  5. Article
  6. Article
  7. Article
  8. Antidepressants for smoking cessation.The Cochrane database of systematic reviews · 2023
    Review
  9. Article
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  14. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ali Ramazan BenliDepartment of Family Medicine, Karabuk University, Medical Faculty, 78000 Karabuk, Turkey.
Selman ErturhanAltinyayla State Hospital, Altinyayla, 58470 Sivas, Turkey.
Muhammet Ali OrucEtimesgut State Hospital, Etimesgut, 06790 Ankara, Turkey.
Pinar KalpakciCekerek Primary Care Unit, Cekerek, 66500 Yozgat Turkey.
Didem SunayDepartment of Family Medicine, Karabuk University, Medical Faculty, 78000 Karabuk, Turkey.
Yeltekin DemirelDepartment of Family Medicine, Cumhuriyet University, Medical Faculty, 58000 Sivas, Turkey.
Karabük University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWithin the context of the support program for smoking cessation, initiated by the Turkish Ministry of Health in 2011, those who present at 'smoking cessation' centres and are found to be suitable for pharmacological treatment are given varenicline and bupropion free of charge. As the smoking cessation programme is centralized, the selection of the medication is made randomly to provide a fixed distribution rate. The aim of this study was to evaluate the efficacy of both varenicline and bupropion in smoking cessation and to evaluate the effect of the smoking cessation programme.

methodsA total of 405 individuals who met the study criteria were included in the study. Smoking habits and degree of dependence were determined in all the participants with the Fagerstrom test for nicotine dependence (FTND) and bupropion or varenicline therapy was initiated in those who were eligible. Patients were followed up at 15 days then at 1, 2, 3, 6 and 12 months after smoking cessation. A level of CO < 5 ppm and 'point prevalence abstinence' were used as the criteria of success for smoking cessation and this evaluation showed the non-smoking status in the previous 7 days.

resultsThe mean age of the participants was 35.19 ± 7.73 years and 82.8% (

conclusionsAlthough the rates of smoking cessation in all the other control points were higher with varenicline than with bupropion, no significant difference was found between the success rates of varenicline and bupropion used in smoking cessation based on the last 7 days at the end of one year. Those who used the medications for 45 days or longer were more successful in smoking cessation.

Indexed as

BupropionSmoking cessationVarenicline

Identifiers

PMID28167895
PMCPMC5286845
OpenAlexW2583714487

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.