Evidence map›Paper›PMID 28167794›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

Gata4 potentiates second heart field proliferation and Hedgehog signaling for cardiac septation.

Lun Zhou, Jielin Liu, Menglan Xiang, Patrick Olson, Alexander Guzzetta, Ke Zhang, Ivan P Moskowitz, Linglin Xie

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 76 citations in OpenAlex.

  1. Review
  2. Article
  3. Case Report: A rare stop-gainedFrontiers in cardiovascular medicine · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. RNA binding proteins in cardiovascular development and disease.Current topics in developmental biology · 2024
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. The second heart field: the first 20 years.Mammalian genome : official journal of the International Mammalian Genome Society · 2023
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Lun ZhouDepartment of Basic Sciences, University of North Dakota, Grand Forks, ND 58202.
Jielin LiuDepartment of Nutrition and Food Sciences, Texas A&M University, College Station, TX 77843.
Menglan XiangDepartment of Basic Sciences, University of North Dakota, Grand Forks, ND 58202.
Patrick OlsonDepartment of Basic Sciences, University of North Dakota, Grand Forks, ND 58202.
Alexander GuzzettaDepartment of Pediatrics, The University of Chicago, Chicago, IL 60637.
Ke ZhangDepartment of Pathology, University of North Dakota, Grand Forks, ND 58202.
Ivan P MoskowitzDepartment of Pediatrics, The University of Chicago, Chicago, IL 60637; linglin.xie@tamu.edu imoskowitz@uchicago.edu.
Linglin XieDepartment of Basic Sciences, University of North Dakota, Grand Forks, ND 58202; linglin.xie@tamu.edu imoskowitz@uchicago.edu.
University of North Dakota · USUniversity of Chicago · USHuazhong University of Science and Technology · CNTexas A&M University · US

Funding

Research CoresP20GM103442 · NIGMS · UNIVERSITY OF NORTH DAKOTA · PI Chris Jurgens · 2012 to 2026
$53.0M
WORKSHOPS AND EVALUATIONP20RR016471 · NCRR · UNIVERSITY OF NORTH DAKOTA · PI KELLER, CHRISTOPHER P · 2001 to 2011
$31.7M
Genetic and Molecular Analysis of Mutants with Congenital Heart DefectsR01HL092153 · NHLBI · UNIVERSITY OF CHICAGO · PI MOSKOWITZ, IVAN PAUL · 2009 to 2017
$4.5M
Training Program in Developmental BiologyT32HD055164 · NICHD · UNIVERSITY OF CHICAGO · PI Sally Horne-Badovinac, Paschalis Kratsios · 2008 to 2026
$3.6M
Etiology of Congenital Heart Disease in Down SyndromeR01HL124836 · NHLBI · UNIVERSITY OF CHICAGO · PI MOSKOWITZ, IVAN PAUL, REEVES, ROGER H · 2014 to 2017
$2.7M
Gene Interaction Study of Tbx5, Hh pathway and Osr1 in atrial septationR15HL117238 · NHLBI · UNIVERSITY OF NORTH DAKOTA · PI ZHANG, KE KURT · 2013 to 2013
$394k
An important role of Osr1 in outflow tract developmentR56HL138479 · NHLBI · TEXAS A&M AGRILIFE RESEARCH · PI XIE, LINGLIN · 2017 to 2017
$367k
NCRR NIH HHS P20 RR016471NHLBI NIH HHS R01 HL092153NHLBI NIH HHS R01 HL124836NHLBI NIH HHS R15 HL117238NHLBI NIH HHS R56 HL138479NICHD NIH HHS T32 HD055164NIGMS NIH HHS P20 GM103442
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsCell CycleCell ProliferationGATA4 Transcription FactorHeartHeart SeptumHedgehog ProteinsMiceMyocardiumSignal TransductionStem CellsTranscription FactorsGata4 protein, mouseGATA4 Transcription FactorHedgehog ProteinsTranscription FactorsASDscell cycleGata4Hedgehog signalingsecond heart field

Identifiers

PMID28167794
PMCPMC5338429
OpenAlexW2587733078

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.