ArticleProceedings of the National Academy of Sciences of the United States of America2017
HY5, a positive regulator of light signaling, negatively controls the unfolded protein response in
Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.
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Who cites it
65 citing papers in PubMed.
- Light-defined cold acclimation reprograms organ-specific metabolic and transcriptional landscapes for salt stress responses in maize.Plant cell reports · 2026Article
- The tomato cytoplasmic receptor-like kinase TPK09 mediates resistance to Botrytis cinerea and tolerance to light-induced stress.Plant physiology · 2026Article
- Unraveling competitive protein interactions: A critical step toward improved production and therapeutics.Journal of advanced research · 2026Review
- Rewiring the unfolded protein response for plant growth recovery after stress.Plant communications · 2026Review
- Arabidopsis HY5 enhances jasmonate responses by directly suppressing the expression of theFrontiers in plant science · 2026Article
- The bZIP transcription factor RISBZ1 balances grain filling and ER stress response in rice grains.Plant communications · 2025Article
- The core morning clock component CCA1 enhances UPR target gene expression to facilitate ER stress recovery.Plant communications · 2025Article
- A genome-wide association study prioritizes VRN1-2 as a candidate gene associated with plant height in soybean.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- VvFHY3 links auxin and endoplasmic reticulum stress to regulate grape anthocyanin biosynthesis at high temperatures.The Plant cell · 2024Article
- Identification of transcription factor co-binding patterns with non-negative matrix factorization.Nucleic acids research · 2024Article
- The VAMP-associated protein VAP27-1 plays a crucial role in plant resistance to ER stress by modulating ER-PM contact architecture in Arabidopsis.Plant communications · 2024Article
- Dynamics of ER stress-induced gene regulation in plants.Nature reviews. Genetics · 2024Review
- Post-translational modifications: emerging directors of cell-fate decisions during endoplasmic reticulum stress in Arabidopsis thaliana.Biochemical Society transactions · 2024Review
- Multi-omics Resources for Understanding Gene Regulation in Response to ER Stress in Plants.Methods in molecular biology (Clifton, N.J.) · 2024Article
- Article
- Review
- Unveiling a differential metabolite modulation of sorghum varieties under increasing tunicamycin-induced endoplasmic reticulum stress.Cell stress & chaperones · 2023Article
- Blue light receptor CRY1 regulates HSFA1d nuclear localization to promote plant thermotolerance.Cell reports · 2023Article
- CRISPR/Cas9-MediatedInternational journal of molecular sciences · 2023Article
- An IRE1-proteasome system signalling cohort controls cell fate determination in unresolved proteotoxic stress of the plant endoplasmic reticulum.Nature plants · 2023Article
5 more citing papers are in PubMed but not listed here.
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Light influences essentially all aspects of plant growth and development. Integration of light signaling with different stress response results in improvement of plant survival rates in ever changing environmental conditions. Diverse environmental stresses affect the protein-folding capacity of the endoplasmic reticulum (ER), thus evoking ER stress in plants. Consequently, the unfolded protein response (UPR), in which a set of molecular chaperones is expressed, is initiated in the ER to alleviate this stress. Although its underlying molecular mechanism remains unknown, light is believed to be required for the ER stress response. In this study, we demonstrate that increasing light intensity elevates the ER stress sensitivity of plants. Moreover, mutation of the ELONGATED HYPOCOTYL 5 (HY5), a key component of light signaling, leads to tolerance to ER stress. This enhanced tolerance of
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.