Evidence map›Paper›PMID 28167675›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2017

ARPP-16 Is a Striatal-Enriched Inhibitor of Protein Phosphatase 2A Regulated by Microtubule-Associated Serine/Threonine Kinase 3 (Mast 3 Kinase).

Erika C Andrade, Veronica Musante, Atsuko Horiuchi, Hideo Matsuzaki, A Harrison Brody, Terence Wu, Paul Greengard, Jane R Taylor, Angus C Nairn

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. A complex of MAST1 and 14-3-3η regulates Tau phosphorylation in the developing cortex.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Article
  4. Saturated fatty acids stimulate cytokine production in tanycytes via the PP2Ac-dependent signaling pathway.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024
    Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Frontiers in genetics · 2021
    Article
  12. Biomolecular NMR assignments · 2020
    Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. cAMP regulation of protein phosphatases PP1 and PP2A in brain.Biochimica et biophysica acta. Molecular cell research · 2019
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Erika C AndradeDepartment of Psychiatry, Yale University School of Medicine, New Haven, Connecticut 06508.
Veronica MusanteDepartment of Psychiatry, Yale University School of Medicine, New Haven, Connecticut 06508.
Atsuko HoriuchiLaboratory of Molecular and Cellular Neuroscience, Rockefeller University, New York, New York 10065, and.
Hideo MatsuzakiDepartment of Psychiatry, Yale University School of Medicine, New Haven, Connecticut 06508.ORCID 0000-0002-6869-1261
A Harrison BrodyLaboratory of Molecular and Cellular Neuroscience, Rockefeller University, New York, New York 10065, and.ORCID 0000-0001-9655-6713
Terence WuKeck Biotechnology Resource Center, Yale University, New Haven, Connecticut 06511.ORCID 0000-0001-6378-2116
Paul GreengardLaboratory of Molecular and Cellular Neuroscience, Rockefeller University, New York, New York 10065, and.
Jane R TaylorDepartment of Psychiatry, Yale University School of Medicine, New Haven, Connecticut 06508.
Angus C NairnDepartment of Psychiatry, Yale University School of Medicine, New Haven, Connecticut 06508, angus.nairn@yale.edu.ORCID 0000-0002-7075-0195
Yale University · USRockefeller University · USW. M. Keck Foundation · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Yale/NIDA Neuroproteomics Research CenterP30DA018343 · NIDA · YALE UNIVERSITY · PI ANGUS C. NAIRN, Kenneth Robert WILLIAMS · 2004 to 2026
$37.1M
THE ROLE OF DARPPS IN THE ACUTE AND CHRONIC EFFECTS OF COCAINE AND AMPHETAMINEP01DA010044 · NIDA · ROCKEFELLER UNIVERSITY · PI GREENGARD, PAUL · 1996 to 2015
$23.6M
Yale Alzheimer Disease Research CenterP50AG047270 · NIA · YALE UNIVERSITY · PI MAROTTOLI, RICHARD · 2015 to 2019
$8.3M
COGNITIVE DYSFUNCTION AFTER CHRONIC PCP, THC AND COCAINER01DA011717 · NIDA · YALE UNIVERSITY · PI TAYLOR, JANE R · 1998 to 2014
$3.4M
Supplement for "Serine/Threonine Phosphatases in Neurological Diseases"R01NS091336 · NINDS · UNIVERSITY OF ARIZONA · PI PAGE, REBECCA, PETI, WOLFGANG · 2015 to 2019
$1.8M
NCATS NIH HHS UL1 TR001863NIA NIH HHS P50 AG047270NIDA NIH HHS P01 DA010044NIDA NIH HHS P30 DA018343NIDA NIH HHS R01 DA011717NINDS NIH HHS R01 NS091336
6 · The paper itself

Abstract

ARPP-16 (cAMP-regulated phospho-protein of molecular weight 16 kDa) is one of several small acid-soluble proteins highly expressed in medium spiny neurons of striatum that are phosphorylated in response to dopamine acting via D1 receptor/protein kinase A (PKA) signaling. We show here that ARPP-16 is also phosphorylated

Indexed as

AnimalsCells, CulturedCorpus StriatumGene Expression Regulation, EnzymologicMaleMiceMice, Inbred C57BLMicrotubule-Associated ProteinsNeuronsPhosphoproteinsPhosphorylationProtein Phosphatase 2Protein Serine-Threonine Kinasescyclic AMP-regulated phosphoprotein 16MAST3 protein, mouseMicrotubule-Associated ProteinsPhosphoproteinsProtein Phosphatase 2Protein Serine-Threonine Kinasescocainedopaminemedium spiny neuronmotivationprotein kinase A

Identifiers

PMID28167675
PMCPMC5354324
OpenAlexW2586711372

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.