Evidence map›Paper›PMID 28167671›Full record

ArticleInfection and immunity2017

Defining the Ail Ligand-Binding Surface: Hydrophobic Residues in Two Extracellular Loops Mediate Cell and Extracellular Matrix Binding To Facilitate Yop Delivery.

Tiffany M Tsang, Jeffrey S Wiese, Jamal A Alhabeil, Lisa D Usselman, Joshua J Thomson, Rafla Matti, Malte Kronshage, Natalie Maricic, Shanedah Williams, Naama H Sleiman and 2 more

Abstract read
In one paragraph

Article in Infection and immunity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Yersinia pestis ΔApplied and environmental microbiology · 2023
    Article
  3. Review
  4. Engineering a HyperstableJournal of the American Chemical Society · 2022
    Article
  5. Article
  6. Article
  7. Bacterial autoaggregation.AIMS microbiology · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Tiffany M TsangDepartment of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Jeffrey S WieseDepartment of Biomedical and Diagnostic Sciences, University of Detroit Mercy School of Dentistry, Detroit, Michigan, USA.
Jamal A AlhabeilDepartment of Biomedical and Diagnostic Sciences, University of Detroit Mercy School of Dentistry, Detroit, Michigan, USA.
Lisa D UsselmanDepartment of Biologic and Materials Sciences, University of Michigan School of Dentistry, Ann Arbor, Michigan, USA.
Joshua J ThomsonDepartment of Biomedical and Diagnostic Sciences, University of Detroit Mercy School of Dentistry, Detroit, Michigan, USA.
Rafla MattiDepartment of Biologic and Materials Sciences, University of Michigan School of Dentistry, Ann Arbor, Michigan, USA.
Malte KronshageDepartment of Biologic and Materials Sciences, University of Michigan School of Dentistry, Ann Arbor, Michigan, USA.
Natalie MaricicDepartment of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Shanedah WilliamsDepartment of Biologic and Materials Sciences, University of Michigan School of Dentistry, Ann Arbor, Michigan, USA.
Naama H SleimanDepartment of Biomedical and Diagnostic Sciences, University of Detroit Mercy School of Dentistry, Detroit, Michigan, USA.
Suleyman FelekDepartment of Biologic and Materials Sciences, University of Michigan School of Dentistry, Ann Arbor, Michigan, USA.
Eric S KrukonisDepartment of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, USA krukones@udmercy.edu.

Funding

Cellular Biotechnology Training Program (CBTP)T32GM008353 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SCHWENDEMAN, ANNA · 1991 to 2021
$9.3M
Role of Yersinia pestis Ail in Yop delivery and plagueR21AI090194 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KRUKONIS, ERIC S · 2011 to 2012
$427k
Evaluation of Ail as a protective immunogen for plagueR03AI092318 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KRUKONIS, ERIC S · 2011 to 2012
$155k
NIAID NIH HHS R03 AI092318NIAID NIH HHS R21 AI090194NIGMS NIH HHS T32 GM008353
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Binding SitesProtein Interaction Domains and MotifsYersinia pestisAmino AcidsAmino Acid SequenceBacterial AdhesionBacterial Outer Membrane ProteinsExtracellular MatrixHost-Pathogen InteractionsHumansHydrophobic and Hydrophilic InteractionsMutationProtein BindingSequence DeletionAmino AcidsBacterial Outer Membrane Proteinsplagueserum resistancetype III secretion

Identifiers

PMID28167671
PMCPMC5364317

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.