Evidence map›Paper›PMID 28167628›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2017

Exposure to a Social Stressor Induces Translocation of Commensal Lactobacilli to the Spleen and Priming of the Innate Immune System.

William P Lafuse, Rachel Gearinger, Sydney Fisher, Connor Nealer, Amy R Mackos, Michael T Bailey

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 49 citations in OpenAlex.

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  7. Social stress induces autoimmune responses against the brain.Proceedings of the National Academy of Sciences of the United States of America · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

William P LafuseDepartment of Microbial Infection and Immunity, The Ohio State University, Columbus, OH 43210.
Rachel GearingerDepartment of Microbial Infection and Immunity, The Ohio State University, Columbus, OH 43210.
Sydney FisherDepartment of Pediatrics, The Ohio State University, Columbus, OH 43210.
Connor NealerDepartment of Microbial Infection and Immunity, The Ohio State University, Columbus, OH 43210.
Amy R MackosCenter for Microbial Pathogenesis, The Research Institute at Nationwide Children's Hospital, Columbus, OH 43210; and.ORCID 0000-0001-9882-3854
Michael T BaileyCenter for Microbial Interface Biology, The Ohio State University, Columbus, OH 43210; Michael.bailey2@nationwidechildrens.org.
Interface (United States) · USNationwide Children's Hospital · US

Funding

Role of Commensal Microbiota in Stressor-Induced ImmunomodulationR21AI107238 · NIAID · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI BAILEY, MICHAEL T · 2014 to 2015
$425k
NIAID NIH HHS R21 AI107238
6 · The paper itself

Abstract

Studies have shown that exposure to psychological stressors leads to inflammation throughout the body. This has been widely studied using social disruption (SDR), a social stressor that involves repeated social defeat in subordinate mice. Exposure to SDR increases serum cytokine levels, results in accumulation of spleen CD11b

Indexed as

Bacterial TranslocationImmunity, InnateAnimalsCells, CulturedEnvironmental ExposureInterleukin-1betaInterleukin-23LactobacillusMaleMiceMice, Inbred C57BLMonocytesNeutrophilsRNA, Ribosomal, 16SSpleenStress, PsychologicalInterleukin-1betaInterleukin-23RNA, Ribosomal, 16S

Identifiers

PMID28167628
PMCPMC5340647
OpenAlexW2586076345

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.