Evidence map›Paper›PMID 28167553›Full record

ArticleAntimicrobial agents and chemotherapy2017

Troponoids Can Inhibit Growth of the Human Fungal Pathogen Cryptococcus neoformans.

Maureen J Donlin, Anthony Zunica, Ashlyn Lipnicky, Aswin K Garimallaprabhakaran, Alex J Berkowitz, Alexandre Grigoryan, Marvin J Meyers, John E Tavis, Ryan P Murelli

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Effects of Troponoids on Mitochondrial Function and Cytotoxicity.Antimicrobial agents and chemotherapy · 2022
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. HBV replication inhibitors.Antiviral research · 2020
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Maureen J DonlinEdward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St. Louis, Missouri, USA donlinmj@slu.edu.
Anthony ZunicaDepartment of Molecular Microbiology and Immunology, Saint Louis University School of Medicine, St. Louis, Missouri, USA.
Ashlyn LipnickyDepartment of Molecular Microbiology and Immunology, Saint Louis University School of Medicine, St. Louis, Missouri, USA.
Aswin K GarimallaprabhakaranDepartment of Chemistry, Brooklyn College, The City University of New York, Brooklyn, New York, USA.
Alex J BerkowitzDepartment of Chemistry, Brooklyn College, The City University of New York, Brooklyn, New York, USA.
Alexandre GrigoryanDepartment of Chemistry, Brooklyn College, The City University of New York, Brooklyn, New York, USA.
Marvin J MeyersCenter for World Health and Medicine, Saint Louis University School of Medicine, St. Louis, Missouri, USA.
John E TavisDepartment of Molecular Microbiology and Immunology, Saint Louis University School of Medicine, St. Louis, Missouri, USA.
Ryan P MurelliDepartment of Chemistry, Brooklyn College, The City University of New York, Brooklyn, New York, USA.

Funding

Development and Exploitation of New Synthetic Strategies for TropolonesSC1GM111158 · NIGMS · BROOKLYN COLLEGE · PI MURELLI, RYAN · 2015 to 2023
$3.1M
Optimization of alpha-hydroxytropolones as novel inhibitors of the HBV RNaseHR01AI122669 · NIAID · SAINT LOUIS UNIVERSITY · PI TAVIS, JOHN E · 2016 to 2020
$2.2M
A screen for antiviral compounds targeting the Hepatitis B Virus ribonuclease HR01AI104494 · NIAID · SAINT LOUIS UNIVERSITY · PI TAVIS, JOHN E · 2014 to 2016
$1.0M
NIAID NIH HHS R01 AI104494NIAID NIH HHS R01 AI122669NIGMS NIH HHS SC1 GM111158
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Amphotericin BAntifungal AgentsCryptococcus neoformansFluconazoleHumansMicrobial Sensitivity TestsTropoloneAmphotericin BAntifungal AgentsFluconazoleTropoloneantifungal agentsCryptococcus neoformanstropolones

Identifiers

PMID28167553
PMCPMC5365692

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.